Belgium | The Netherlands | The United States | The United Kingdom | Brazil | South Africa | Vietnam | Ethiopia | |
---|---|---|---|---|---|---|---|---|
Number of participants | 1 | 1 | 1 | 1 | 4 | 4 | 1 | 1 |
Country income level | High | High | High | High | Upper-middle | Upper-middle | Lower-middle | Low |
MDR-TB burden | Low | Low | Low | Low | Low | High | High | High |
BDQ registration | Registered | Registered | Registered | Registered | Registered | Registered | Registration pending | Registered |
National BDQ eligibility guideline | Not publicly available | Patients with RR-TB | Patients \(\ge\) 6 years and weighing \(\ge\) 15 kg with pulmonary MDR-TB | Patients \(\ge\) 6 years with RR-TB | Patients with RR-TB | Patients \(\ge\) 6 years and weighing \(\ge\) 15 kg with RR-TB | Patients \(\ge\) 6 years with RR-TB and without high risk of cardiovascular complication, severe liver disease and severe electrolyte disorder | Patients \(\ge\) 6 years with RR-TB |
Conditions for BDQ access | After approval from national TB Consilium | After referral to national reference center | After BDQ order from treating physician is accepted by Metro Medical or Johnson & Johnson Patient Assistance Foundation | After approval from national TB Consilium | As part of operational research (until October 2021) | At all health facilities | Compassionate use after approval from hospital scientific committee | After referral to one of 60 MDR-TB Treatment Initiation Centers |
Cost of BDQ (cost for 6 months) | High (~ $22,000) | High (~ $22,000) | High (~ $30,000) | High (~ $22,816) | Low ($340) | Low ($400) | Low ($340) | Low ($340) |
Access to WGS for DST | Routine | Routine | Routine | Routine | Research | Research | Research | Research |