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Table 2 Underlying conditions among patients with candidemia, Alameda County, 2017–2020

From: Epidemiologic features, clinical characteristics, and predictors of mortality in patients with candidemia in Alameda County, California; a 2017–2020 retrospective analysis

 

Level

Overall

2017

2018

2019

2020

Number

 

392

83

108

97

104

Previous candidemia (%)

No

382 (97)

83 (100)

104 (96)

91 (94)

104 (100)

Yes

10 (3)

0 (0)

4 (4)

6 (6)

0 (0)

Hospitalization 90 days before culture (%)

No

187 (48)

33 (40)

46 (43)

56 (58)

52 (50)

Yes

188 (48)

46 (55)

56 (52)

40 (41)

46 (44)

Unk

17 (4)

4 (5)

6 (6)

1 (1)

6 (6)

Chronic kidney disease (%)

No

289 (74)

59 (71)

74 (68)

74 (76)

82 (79)

Yes

103 (26)

24 (29)

34 (32)

23 (24)

22 (21)

Chronic liver disease (%)

No

332 (85)

75 (90)

89 (82)

80 (82)

88 (85)

Yes

60 (15)

8 (10)

19 (18)

17 (18)

16 (15)

Chronic lung disease (%)

No

292 (74)

68 (82)

77 (71)

66 (68)

81 (78)

Yes

100 (26)

15 (18)

31 (29)

31 (32)

23 (22)

Diabetes mellitus (%)

No

234 (60)

54 (65)

59 (55)

62 (64)

59 (57)

Yes

158 (40)

29 (35)

49 (45)

35 (36)

45 (43)

Pregnancy (%)

No

389 (99)

83 (100)

107 (99)

96 (99)

103 (99)

Yes

3 (1)

0 (0)

1 (1)

1 (1)

1 (1)

Obesity (%)

No

353 (90)

73 (88)

102 (94)

85 (88)

93 (89)

Yes

39 (10)

10 (12)

6 (6)

12 (12)

11 (11)

Total parenteral nutrition (%)

No

323 (84)

59 (79)

87 (81)

83 (86)

94 (90)

Yes

60 (16)

16 (21)

20 (19)

14 (14)

10 (10)

Systemic antibiotics 14 days before culture (%)

No

75 (19)

9 (11)

14 (13)

28 (29)

24 (23)

Yes

311 (81)

71 (89)

91 (87)

69 (71)

80 (77)

Systemic antifungals 14 days before culture (%)

No

285 (73)

17 (20)

95 (90)

83 (86)

90 (87)

Yes

104 (27)

66 (80)

11 (10)

14 (14)

13 (13)

Central venous catheter (%)

No

139 (36)

25 (30)

34 (32)

37 (38)

43 (41)

Yes

252 (64)

58 (70)

74 (68)

59 (61)

61 (59)

Unk

1 (0)

0 (0)

0 (0)

1 (1)

0 (0)

Pancreatitis (%)

No

369 (94)

79 (95)

101 (94)

92 (95)

97 (93)

Yes

23 (6)

4 (5)

7 (6)

5 (5)

7 (7)

Neutropenia (%)

No

287 (94)

60 (91)

70 (95)

77 (94)

80 (96)

Yes

18 (6)

6 (9)

4 (5)

5 (6)

3 (4)

ICU admission 14 days before culture (%)

No

206 (53)

42 (52)

61 (58)

47 (49)

56 (54)

Yes

180 (47)

38 (48)

45 (42)

49 (51)

48 (46)

HIV infection (%)

No

380 (97)

81 (98)

105 (97)

93 (96)

101 (97)

Yes

12 (3)

2 (2)

3 (3)

4 (4)

3 (3)

Cirrhosis of the liver (%)

No

354 (90)

77 (93)

97 (90)

87 (90)

93 (89)

Yes

38 (10)

6 (7)

11 (10)

10 (10)

11 (11)

Solid organ transplant (%)

No

390 (100)

82 (99)

108 (100)

97 (100)

103 (99)

Yes

2 (0)

1 (1)

0 (0)

0 (0)

1 (1)

No surgery 90 days before culture (%)

No

80 (20)

25 (30)

23 (21)

17 (18)

15 (14)

Yes

312 (80)

58 (70)

85 (79)

80 (82)

89 (86)

Abdominal surgery 90 days before culture (%)

0

341 (87)

64 (77)

95 (88)

89 (92)

93 (89)

1

51 (13)

19 (23)

13 (12)

8 (8)

11 (11)

Nonabdominal surgery 90 days before culture (%)

No

361 (92)

75 (90)

98 (91)

88 (91)

100 (96)

Yes

31 (8)

8 (10)

10 (9)

9 (9)

4 (4)

Hematologic malignancy (%)

No

372 (95)

81 (98)

103 (95)

92 (95)

96 (92)

Yes

20 (5)

2 (2)

5 (5)

5 (5)

8 (8)

Solid organ malignancy (%)

No

356 (91)

71 (86)

97 (90)

89 (92)

99 (95)

Yes

36 (9)

12 (14)

11 (10)

8 (8)

5 (5)

Metastatic solid organ malignancy (%)

No

351 (90)

73 (88)

97 (90)

88 (91)

93 (89)

Yes

41 (10)

10 (12)

11 (10)

9 (9)

11 (11)

  1. Unk unknown