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Table 1 Baseline maternal and child characteristics at 6-weeks postpartum by peripartum antiretroviral exposure, 2012–2014, South Africa

From: Impact of antenatal antiretroviral drug exposure on the growth of children who are HIV-exposed uninfected: the national South African Prevention of Mother to Child Evaluation cohort study

Maternal characteristic

Total N = 2526

Pre-conception ART N = 617

Post-conception ART N = 782

AZT prophylaxis N = 879

None N = 189

Newly infected mothers N = 59

 

n (%)

n (%)

n (%)

n (%)

n (%)

n (%)

Age (years)

      

 13–19

109 (4.32)

13 (2.11)

23 (2.94)

58 (6.60)

11 (5.82)

4 (6.78)

 20–35

2063 (81.67)

449 (72.77)

668 (85.42)

738 (83.96)

160 (84.66)

48 (81.36)

 35+

354 (14.01)

155 (25.12)

91 (11.64)

83 (9.44)

18 (9.52)

7 (11.86)

Parity

      

 Primipara

588 (23.28)

95 (15.40)

188 (24.04)

255 (29.01)

31 (16.40)

19 (32.20)

 Multipara

1938 (76.72)

522 (84.60)

594 (75.96)

594 (70.99)

158 (83.60)

40 (67.80)

Education (grade)

      

 None-grade 7

490 (19.40)

142 (23.01)

138 (17.65)

146 (16.61)

51 (26.98)

13 (22.03)

 7–12

1935 (76.60)

456 (73.91)

617 (78.90)

687 (78.16)

131 (69.31)

44 (74.58)

 12+

101 (4.25)

19 (3.08)

27 (3.45)

46 (5.23)

7 (3.70)

2 (4.25)

Delivery mode

      

 Vaginal

1920 (76.16)

456 (73.91)

577 (74.16)

686 (78.04)

154 (81.91)

47 (76.16)

 C-section

601 (23.84)

161 (26.09)

201 (25.84)

193 (21.96)

34 (18.09)

12 (23.84)

 Missing

5

0

4

0

1

0

CD4 count at 6 weeks, n, median cells/mm3(IQR)

1587, 373 (268–508)

417, 350 (250–500)

514, 271 (186–340)

562, 480 (390–598)

93, 495(367–600)

1, 734 (734–734)

ANC visits

      

 1–5

1031 (60.15)

247 (56.39)

303 (58.83)

359 (60.95)

90 (69.23)

32 (76.19)

 5+

683 (39.85)

191 (43.61)

212 (41.17)

230 (39.05)

40 (30.77)

10 (23.81)

 Missing

812

179

267

290

59

17

Syphilis (antenatal)

      

 Positive

159 (8.91)

52 (11.82)

57 (10.12)

42 (6.65)

8 (7.21)

0 (0)

 Negative

1625 (91.09)

388 (88.18)

506 (89.88)

590 (93.35)

103 (92.79)

38 (100)

 Missing

742

177

219

247

78

21

Current tuberculosis

      

 Yes

128 (5.09)

59 (9.61)

42 (5.40)

21 (2.39)

5 (2.66)

1 (1.69)

 No

2388 (94.91)

555 (90.39)

736 (94.60)

856 (97.61)

183 (97.34)

58 (98.31)

 Missing

10

3

4

2

1

0

Place of delivery

      

 Hospital

1973 (78.11)

497 (80.55)

618 (79.03)

683 (77.70)

128 (67.72)

47 (79.66)

 Clinic

449 (17.78)

95 (15.40)

148 (18.93)

159 (18.09)

39 (20.63)

8 (13.56)

 Home

104 (4.12)

25 (4.05)

16 (2.05)

37 (4.21)

22 (11.64)

4 (6.78)

Birth attendant

      

 Doctor

728 (28.82)

186 (30.15)

238 (30.43)

243 (27.65)

43 (22.75)

18 (30.51)

 Nurse

1704 (67.46)

409 (66.29)

531 (67.90)

602 (68.49)

125 (66.14)

37 (62.71)

 TBA

94 (3.72)

22 (3.57)

13 (1.66)

34 (3.87)

21 (11.11)

4 (6.78)

Peri-partum social support

      

 Yes

1969 (77.95)

488 (79.09)

604 (77.24)

676 (76.91)

153 (80.95)

48 (81.36)

 No

557 (22.05)

129 (20.91)

178 (22.76)

203 (23.09)

36 (19.05)

11 (18.64)

Mother employed

      

 Yes

501 (19.83)

143 (23.18)

168 (21.48)

153 (17.41)

25 (13.23)

12 (20.34)

 No

2025 (80.17)

474 (76.82)

614 (78.52)

726 (82.59)

164 (86.77)

47 (79.66)

Male

1285 (50.87)

310 (50.24)

386 (49.36)

465 (52.90)

91 (48.15)

33 (55.93)

Female

1241 (49.13)

307 (49.76)

396 (50.64)

414 (47.10)

98 (51.85)

26 (44.07)

Piped water

      

 Yes

1913 (75.73)

479 (77.63)

596 (76.21)

660 (75.09)

139 (73.54)

39 (66.10)

 No

613 (24.27)

138 (22.37)

186 (23.79)

219 (24.91)

50 (26.46)

20 (33.90)

Flush toilet

      

 Yes

1350 (53.44)

359 (58.18)

426 (54.48)

466 (53.01)

69 (36.51)

30 (50.85)

 No

1176 (46.56)

258 (41.82)

356 (45.52)

413 (46.99)

120 (63.49)

29 (49.15)

Electricity

      

 Yes

2377 (94.10)

585 (94.81)

747 (95.52)

815 (92.72)

173 (91.53)

57 (96.61)

 No

149 (5.90)

32 (5.19)

35 (4.48)

64 (7.28)

16 (8.47)

2 (3.39)

No food in house

      

 Yes

496 (19.64)

139 (22.53)

143 (18.29)

174 (19.80)

31 (16.40)

9 (15.25)

 No

2027 (80.25)

478 (77.47)

638 (81.59)

703 (79.98)

158 (83.60)

50 (84.75)

Child sex

      

 Male

1285 (50.87)

310 (50.24)

386 (49.36)

465 (52.90)

91 (48.15)

33 (55.93)

 Female

1241 (49.13)

307 (49.76)

396 (50.64)

414 (47.10)

98 (51.85)

26 (44.07)

Breastfed at 6 weeks

      

 Yes

1647 (66.84)

374 (61.61)

504 (65.88)

589 (68.97)

131 (71.98)

49 (87.50)

  1. ANC: antenatal care; ART: antiretroviral therapy (Maternal ART regimens generally consisted of Tenofovir, Lamivudine or Emtricitabine and Nevirapine); AZT: Azidothymidine; HEU: HIV exposed uninfected; None: children with no foetal ARV exposure; SD: standard deviation