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Table 2 Trim and fill analysis of overall pooled prevalence of hepatotoxicity among HIV-infected patients in Ethiopia, 2022

From: Prevalence of hepatotoxicity among HIV-infected patients in Ethiopia: a systematic review and meta-analysis

Meta-analysisa

Method

Pooled est

95% CI

Z-value

p-value

No. of studies

Fixed

19.58

18.33–20.83

30.683

 < 0.001

13

Random

25.45

20.06–30.84

9.250

 < 0.001

Iteration

Estimate

Tn

# to trim

Diff

1

19.58

69

4

91

2

16.94

80

6

22

3

15.71

83

6

6

4

15.71

83

6

0

Filled meta-analysisb

Method

Pooled est

95% CI

Z-value

p-value

No. of studies

Fixed

15.71

14.58–16.84

27.32

< 0.001

19

Random

16.416

10.63–22.20

5.558

< 0.001

  1. aTest for heterogeneity: Q = 191.844 on 12 degrees of freedom (p = 0.000)
  2. Trimming estimator: Linear
  3. Meta-analysis type: Fixed-effects mode
  4. bTest for heterogeneity: Q = 426.787 on 18 degrees of freedom (p ≤ 0.001)
  5. Moment-based estimate of between studies variance = 153.14
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BMC Infectious Diseases

ISSN: 1471-2334

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