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Table 7 Multivariable logistic regression analysis for 28-day mortality in patients with sepsis due to IAI

From: Clinical outcomes and prognostic factors of patients with sepsis caused by intra-abdominal infection in the intensive care unit: a post-hoc analysis of a prospective cohort study in Korea

Variable

Univariable

Multivariable

 

OR (95% CI)

P-value

OR (95% CI)

P-value

Age (years), mean (± SD)

1.01 (0.98–1.03)

0.581

  

BMI (kg/m2), mean (± SD)

1.04 (0.97–1.12)

0.239

  

Charlson comorbidity index, mean (± SD)

1.13 (1.00–1.26)

0.039

  

Septic shock, n (%)

1.94 (1.07–3.51)

0.029

  

Initial lactate level (mmol/L), mean (± SD)

1.19 (1.09–1.3)

 < 0.001

  

Initial SOFA score, mean (± SD)

1.24 (1.12–1.36)

 < 0.001

  

SAPS 3 score, mean (± SD)

1.05 (1.03–1.08)

 < 0.001

1.04 (1.02–1.07)

 < 0.001

CRRT, n (%)

109.58 (24.89–482.48)

 < 0.001

7.71 (3.76–15.82)

 < 0.001

Bacteremia, n (%)

1.09 (0.61–1.95)

0.780

  

Time zero to time of antibiotic administration (min)

1.00 (1.00–1.01)

0.330

  

Source control, n (%)

2.38 (1.26–4.51)

0.008

2.02 (0.95–4.30)

0.069

Source control time (h), mean (± SD)

1.00 (1.00–1.00)

0.660

  

Number of organ dysfunction, n (%)

1.66 (1.30–2.13)

 < 0.001

  

MDR, n (%)

0.61 (0.32–1.17)

0.136

  
  1. IAI intra-abdominal infection, OR odds ratio, CI confidence interval, BMI body mass index, SOFA Sequential Organ Failure Assessment, SAPS 3 simplified acute physiology score III, CRRT continuous renal replacement therapy, MDR multidrug resistance
  2. Multiple logistic: C-statistics = 0.83, Hosmer–Lemeshow test p = 0.53