A pragmatic randomized controlled trial of rapid on-site influenza and respiratory syncytial virus PCR testing in paediatric and adult populations

Table 2 Oseltamivir utilization for inpatients

Alberta Children’s Hospital
	ROST	Standard	p value
Percent with oseltamivir prescription^a
All results	11.6 (7.72–17.1)	24.7 (19.2–31.3)	0.0013
Flu positive	68.2 (47.3–83.6)	76.0 (56.6–88.5)	0.75
Flu negative	3.77 (1.74–7.99)	17.2 (12.2–23.6)	< 0.0001
Mean number of doses^b
All results	4.29 (3.61–4.97)	4.97 (5.02–6.60)	0.15
Flu positive	5.33 (4.54–6.13)	8.79 (7.07–10.5)	0.079
Flu negative	1.67 (1.33–2.00)	3.72 (3.36–4.09)	0.0005
Mean hours from admission to first dose^b
All results	14.1 (11.9–16.3)	22.4 (19.4–25.4)	0.029
Flu positive	16.7 (13.9–19.4)	34.4 (28.1–40.6)	0.016
Flu negative	6.65 (4.88–8.40)	10.1 (8.69–11.6)	0.014

Peter Lougheed Centre
	ROST	Standard	p value
Percent with oseltamivir prescription^a
Any result	24.2 (18.2–31.5)	34.2 (27.7–41.6)	0.054
Flu positive	81.8 (61.5–92.7)	73.1 (53.9–86.3)	0.52
Flu negative	14.9 (9.87–21.9)	27.5 (21.0–35.2)	0.0135
Mean number of doses^b
Any result	5.16 (4.51–5.80)	5.53 (5.12–5.95)	0.63
Flu positive	7.72 (6.73–8.68)	8.47 (7.67–9.28)	0.55
Flu negative	2.85 (2.39–3.32)	4.17 (3.85–4.49)	0.022
Mean hours from admission to first dose^b
All results	15.4 (12.5–18.2)	28.4 (19.1–37.8)	0.19
Flu positive	14.6 (10.1–19.2)	22.3 (17.2–27.4)	0.27
Flu negative	16.0 (12.3–19.7)	31.3 (17.8–44.8)	0.28

Data are in proportion(%) (95% CI) or mean (standard error of the mean). ROST= Rapid on-site testing
Alberta Children's Hospital: All results: ROST n = 181, standard n = 194. Flu positive: ROST n = 22, standard n = 25. RSV positive: ROST n = 40, standard n = 38. Flu and RSV negative: ROST n = 119, standard n = 131
Peter Lougheed Centre: All results: ROST n = 157, standard n = 175. Flu positive: ROST n = 22, standard n = 26. RSV positive: ROST n = 11, standard n = 9. Flu and RSV negative: ROST n = 124, standard n = 140
^aStatistical analysis done using Fisher’s exact test
^bStatistical analysis done using unpaired t-test assuming Gaussian distribution with two-tailed p value

ISSN: 1471-2334