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Table 3 Performance evaluation of BSI-HMGS combined with the pre-treatment protocol on whole blood samples

From: Rapid and precise identification of bloodstream infections using a pre-treatment protocol combined with high-throughput multiplex genetic detection system

Pathogens

HMGS

Reference results

PPA

NPA

OPA

 

+

−

 

K. pneumoniae

+

3

0

0.750

1.000

0.995

 

−

1

210

   

P. aeruginosa

+

2

0

1.000

1.000

1.000

 

−

0

212

   

E. cloacae complex

+

1

0

1.000

1.000

1.000

 

−

0

213

   

E. coli

+

3

0

1.000

1.000

1.000

 

−

0

211

   

A. baumannii

+

1

0

1.000

1.000

1.000

 

−

0

213

   

S. maltophilia

+

1

0

1.000

1.000

1.000

 

−

0

213

   

Staphylococcus

+

2

0

0.667

1.000

0.995

 

−

1

211

   

S. aureus

+

2

0

1.000

1.000

1.000

 

−

0

212

   

Streptococcus

+

2

0

1.000

1.000

1.000

 

−

0

212

   

E. faecalis

+

1

0

1.000

1.000

1.000

 

−

0

213

   

E. faecium

+

1

0

1.000

1.000

1.000

 

−

0

213

   

C.albicans

+

2

0

0.667

1.000

0.995

 

−

1

211

   

C. glabrata

+

1

0

1.000

1.000

1.000

 

−

0

213

   
  1. The number of Staphylococcus and Streptococcus represent the number of pathogens with a single Staphylococcus and Streptococcus peak, respectively, excluding the two-peak pathogens. HMGS: high-throughput multiplex genetic detection system; PPA: positive percent agreement; NPA: negative percent agreement; OPA: overall percent agreement