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Table 4 Percentage of populations of viable and non‑viable cells exhibiting structural properties of different cell death types following exposure to different groups of nanoliposomes for 24 h

From: Preparation, characterization, and in-vitro cytotoxicity of nanoliposomes loaded with anti-tubercular drugs and TGF-β1 siRNA for improving spinal tuberculosis therapy

Treatment group

Viable cells

Non-viable cells

Necrosis

Late apoptosis

Early apoptosis

Untreated cells

91.56 ± 0.87

2.65 ± 0.16

4.52 ± 0.72

1.26 ± 0.12

HRZ

90.83 ± 1.65

1.04 ± 0.20

4.48 ± 1.31

3.64 ± 0.55

HRZ/siNC

91.36 ± 1.27

1.45 ± 0.84

3.83 ± 0.60

3.36 ± 0.32

HRZ/siTGF-β1 (35 mg/ml)

84.16 ± 1.53**

1.77 ± 0.29

9.56 ± 0.51

4.48 ± 1.28

HRZ/siTGF-β1 (40 mg/ml)

78.53 ± 1.13**

2.74 ± 0.39

12.50 ± 0.75

6.20 ± 1.16

  1. The results are presented as the average percentage of the cell population (%) ± standard deviation; *P < 0.05 *, *P < 0.01 vs. untreated cells
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BMC Infectious Diseases

ISSN: 1471-2334

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