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Table 1 The clinical features of patients with pyogenic spondylitis caused by Klebsiella pneumoniae

From: Pyogenic spondylitis caused by Klebsiella pneumoniae: should the possibility of hypervirulent Klebsiella pneumoniae be considered?

 

Case 1

Case 2

Case 3

Case 4

Case 5

Case 6

Age

67

60

52

84

61

78

Sex

M

M

F

M

M

M

Underlying disease

Colon cancer

DM, hypertension

No

No

Liver cirrhosis, CKD

DM

Type of infection

CAI

CAI

CAI

CAI

CAI

CAI

Spinal procedure

      

Vertebroplasty

Not done

Not done

Not done

Not done

Not done

Not done

Prosthesis

Not done

Not done

Not done

Not done

Not done

Not done

Source of infection

No

No

No

UTI

No

Liver abscess

Neurologic staging

Stage 1

Stage 1

Stage 1

Stage 2

Stage 2

Stage 2

Radiologic finding

      

Involved area

T-spine

T-spine

L-S spine

L-S spine

L-S spine

L-S spine

Involved number

1 to 2 VB

1 to 2 VB

1 to 2 VB

1 to 2 VB

1 to 2 VB

> 5 VB

Combined abscess

Epidural abscess

No

No

Epidural, psoas abscess

Epidural, psoas abscess

Epidural, psoas abscess

Laboratory finding

      

WBC(103/µL)

15.00

9.37

18.57

22.15

8.03

7.97

CRP(mg/L)

22

129

362

204

215

281

Procalcitonin(ng/mL)

Not checked

0.26

12.41

0.85

74.76

62.78

Bacteremia

No

No

Yes

Yes

Yes

Yes

Tissue culture and sensitivity

Yes

Yes

No

Yes

No

No

Symptoms and signs

      

Fever

No

Yes

Yes

Yes

Yes

Yes

Back pain

Yes

Yes

Yes

Yes

Yes

Yes

Metastatic infection

No

No

Pneumonia

Pneumonia

No

No

Outcome

      

30-day mortality

Alive

Alive

Alive

Dead

Alive

Alive

Sequalae

No

Yes

No

N.A

Yes

Yes

Recur

No

No

No

N.A

No

No

Treatment

      

Antibiotics

CAZ IV

CRO IV, LVX PO

CRO IV, CIP PO

VAN IV, MEM IV

CTX IV, CIP PO

CRO IV, CIP PO

Duration

6 weeks

4 weeks, 3 months

7 weeks, 2 months

2 weeks

2 weeks, 7 months

7 weeks, 3 months

Operation

Not done

Not done

Not done

Not done

Not done

Not done

  1. CAI, community acquired infection; CKD, chronic kidney disease; DM, diabetes mellitus; UTI, urinary tract infection; VB, vertebral body; WBC, white blood cells; CRP, C-reactive protein; CAZ, ceftazidime; CRO, ceftriaxone; LVX, levofloxacin; CIP, ciprofloxacin; VAN, vancomycin; MEM, meropenem; CTX, cefotaxime; IV, intravenous, PO; oral