Table 3 Length of stay, length of ICU stay, and duration of mechanical ventilation during Delta, Delta to Omicron, and Omicron periods, adjusted for age, gender, and Elixhauser comorbidity index
Total | SARI- | SARI+ | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cohort | Mean (SD) | Median (IQR) | Coefficient (95% CI) | P value | Mean (SD) | Median (IQR) | Coefficient (95% CI) | P value | Mean (SD) | Median (IQR) | Coefficient (95% CI) | P value |
Length of stay | ||||||||||||
Delta | 5.5 ± 3.8 | 4.0 [3, 7] | 4.1 ± 3.3 | 3.0 [2, 5] | 6.3 ± 3.8 | 6.0 [3, 8] | ||||||
Delta to Omicron | 4.9 ± 3.8 | 4.0 [2, 7] | -0.06 (-0.10 to -0.02) | < 0.01 | 3.6 ± 3.1 | 3.0 [2, 5] | -0.03 (-0.09 to 0.03) | 0.31 | 6.1 ± 4.1 | 5.0 [3, 8] | -0.02 (-0.08 to 0.03) | 0.41 |
Omicron | 3.9 ± 3.1 | 3.0 [2, 5] | -0.16 (-0.20 to -0.12) | < 0.01 | 3.4 ± 2.8 | 2.0 [2, 4] | -0.04 (-0.09 to 0.01) | 0.16 | 5.1 ± 3.6 | 4.0 [2, 7] | -0.14 (-0.20 to -0.08) | < 0.01 |
Length of stay at ICU* | ||||||||||||
Delta | 4.5 ± 3.6 | 3.0 [2, 6] | 2.7 ± 2.3 | 2.0 [1, 3] | 4.9 ± 3.8 | 4.0 [2, 7] | ||||||
Delta to Omicron | 4.2 ± 3.7 | 3.0 [1, 6] | -0.11 (-0.27 to 0.04) | 0.15 | 1.8 ± 1.3 | 1.0 [1, 2] | -0.33 (-0.56 to -0.10) | < 0.01 | 5.3 ± 4.0 | 4.0 [2, 7] | 0.10 (-0.09 to 0.28) | 0.30 |
Omicron | 3.2 ± 3.2 | 2.0 [1, 4] | -0.36 (-0.52 to -0.20) | < 0.01 | 1.9 ± 1.5 | 1.0 [1, 2] | -0.26 (-0.47 to -0.05) | 0.02 | 4.5 ± 3.9 | 3.0 [2, 6] | -0.14 (-0.35 to 0.08) | 0.21 |
Duration of mechanical ventilation† | ||||||||||||
Delta | 104.7 ± 87.9 | 83.0 [37, 149] | 67.7 ± 63.5 | 70.0 [36, 100] | 105.4 ± 88.3 | 83.5 [37, 150] | ||||||
Delta to Omicron | 95.1 ± 95.5 | 58.0 [22, 154] | -0.34 (-0.69 to 0.01) | 0.06 | 23.7 ± 18.6 | 26.0 [15, 34] | -1.10 (-2.67 to 0.47) | 0.23 | 97.5 ± 96.1 | 61.0 [22, 154] | -0.33 (-0.68 to 0.03) | 0.08 |
Omicron | 78.0 ± 88.3 | 41.0 [12, 135] | -0.61 (-1.05 to -0.17) | < 0.01 | 42.9 ± 30.8 | 36.0 [26, 52] | -0.35 (-1.62 to 0.93) | 0.61 | 83.8 ± 93.5 | 41.5 [10, 154] | -0.65 (-1.12 to -0.18) | < 0.01 |