Table 2 Characteristics of UTI-related antimicrobial users who did / did not have an E. coli positive blood culture during study period 2009–2012

N

1,093,227

1,085,742

7485 (0.7%)

Gender

Female

Male

782,253 (71.6%)

310,974 (28.4%)

777,775 (99.4%)

307,967 (99.0%)

4478 (0.6%)

3007 (1.0%)

Age category at sample

16-34

35-49

50-64

 > 65

268,896 (24.6%)

242,173 (22.2%)

247,287 (22.6%)

334,871 (30.6%)

268,610 (99.9%)

241,693 (99.8%)

246,045 (99.5%)

329,394 (98.4%)

286 (0.1%)

480 (0.2%)

1242 (0.5%)

5477 (1.6%)

Mean age at sample

Mean(SD)

51.8 (20.6)

51.6 (20.5)

70.9 (15.6)

SIMD quintile (Q1 = Most Deprived, Q5 = Least Deprived)

Q1

Q2

Q3

Q4

Q5

247,671 (22.8%)

232,451 (21.4%)

215,015 (19.8%)

198,832 (18.3%)

190,210 (17.5%)

245,735 (99.2%)

230,731 (99.3%)

213,604 (99.3%)

197,581 (99.4%)

189,084 (99.4%)

1936 (0.8%)

1720 (0.7%)

1411 (0.7%)

1251 (0.6%)

1126 (0.6%)

Long-term users of any antimicrobials

No

Yes

1,008,191 (92.2%)

85,036 (7.8%)

1,002,338 (99.4%)

83,404 (98.1%)

5853 (0.6%)

1632 (1.9%)

Treatment failures

No

Yes

898,043 (82.1%)

195,184 (17.9%)

892,839 (99.4%)

192,903 (98.8%)

5204 (0.6%)

2281 (1.2%)

Patients receiving sentinel antimicrobials

Amoxicillin

Ciprofloxacin

Amoxicillin/clavulanic acid

Nitrofurantoin

Trimethoprim

Excl.Amoxicillin^a

UTI-Specific^b

449,099 (41.1%)

260,266 (23.8%)

335,784 (30.7%)

244,612 (22.4%)

669,400 (61.2%)

1,092,151 (99.9%)

752,225 (68.8%)

445,529 (99.2%)

257,583 (99.0%)

333,095 (99.2%)

241,754 (98.8%)

664,343 (99.2%)

1,084,667 (99.3%)

746,421 (99.2%)

3570 (0.8%)

2683 (1.0%)

2689 (0.8%)

2858 (1.2%)

5057 (0.8%)

7484 (0.7%)

5804 (0.8%)