From: Analysis of antibiotic use and clinical outcomes in adults with known and suspected pleural empyema
Demographic features | Total (n = 338) | Clinically resolved (n = 310) | Clinically not resolved (n = 28) | p-value |
---|---|---|---|---|
Age | 58.4 ± 15.3 | 61.0 ± 15.8 | 0.870 | |
Male sex | 209 (61.8%) | 187 (60.3%) | 22 (78.6%) | 0.057 |
Diabetes | 86 (25.4%) | 76 (24.5%) | 10 (35.7%) | 0.193 |
Lung disease (asthma, COPD, or bronchiectasis) | 120 (35.5%) | 106 (34.2%) | 14 (50.0%) | 0.094 |
Glomerular filtration rate ≤ 60 | 63 (18.6%) | 58 (18.7%) | 5 (17.8%) | 0.912 |
Chest tube duration (days; chest tube group only) | 8.6 ± 15.2 | 13.3 ± 16.4 | 0.201 | |
Duration of antibiotics prior to drainage (days) | 6.4 ± 6.5 | 5.5 ± 6.8 | 0.487 | |
ICU admission | 132 (39.1%) | 122 (39.4%) | 10 (35.7%) | 0.657 |
Subgroups | ||||
Drainage via chest tube alone (without surgery) | 192 (56.8%) | 173 (55.8%) | 19 (67.9%) | 0.218 |
Positive pleural culture | 171 (50.6%) | 157 (50.6%) | 14 (50.0%) | 0.904 |