Table 4 Univariate and multivariate analysis of risk factors for mortality in HSCT patients with BC infection
Variable | Survival (n = 14) | Mortality (n = 18) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|---|
P-value | HR (95% CI) | P-value | ||||
Gender, n (%) | 0.195 | Â | Â | |||
 Male, n (%) | 9 (64.3) | 16 (88.9) |  | – | – | |
 Female, n (%) | 5 (35.7) | 2 (11.1) |  |  |  | |
Age < 14 or ≥ 50 years, n (%) | 10 (71.4) | 7 (38.9) | 0.087 | – | – | |
Hematopoietic reconstruction time > 15 days, n (%) | 6 (42.9) | 8 (44.4) | 1.000 | – | – | |
aGVHD, n (%) | 8 (57.1) | 17 (94.4) | 0.027* | 1.68 (0.18–15.24) | 0.646 | |
Total bilirubin > 34.2 µmol/L, n (%) | 2 (14.3) | 4 (22.2) | 0.672 | – | – | |
PCT > 10 µg/L, n (%) | 0 (0) | 10 (55.6) | 0.001* | 40.88 (6.51-256.63) | 0.000* | |
Irrational empiric anti-infective therapy, n (%) | 1 (7.1) | 9 (50) | 0.019* | 2.13 (0.62–7.34) | 0.231 | |
Mechanical ventilation, n (%) | 1 (7.1) | 10 (55.6) | 0.008* | 2.75 (0.75–10.09) | 0.127 | |
Septic shock, n (%) | 2 (14.3) | 12 (66.7) | 0.005* | 4.08 (1.02–16.33) | 0.047* | |
Admission to ICU, n (%) | 6 (42.9) | 14 (77.8) | 0.068 | – | – | |