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Table 2 Laboratory findings at ICU admission

From: Association between active cytomegalovirus infection and lung fibroproliferation in adult patients with acute respiratory distress syndrome: a retrospective study

Laboratory findings

Total

Active CMV infection

P

N = 87

Yes (n = 14, 16.1%)

No (n = 73, 83.9%)

Oxygenation (P/F)

126 (79–183)

118 (77–171)

128 (80–185)

0.524

White blood cells (109/L)

11.3 (7.5–15.0)

9.7 (6.9–14.0)

11.6 (7.6–15.1)

0.407

Neutrophils (109/L)

10.6 (6.6–14.0)

8.9 (6.6–12.2)

10.8 (6.7–14.4)

0.538

Lymphocytes (109/L)

0.4 (0.2–0.7)

0.4 (0.1–0.5)

0.4 (0.2–0.8)

0.224

Monocytes (109/L)

0.5 (0.2–1.0)

0.4 (0.1–0.6)

0.6 (0.2–1.1)

0.115

Hemoglobin (g/L)

93 (79–108)

84 (78–95)

96 (81–112)

0.072

Plateleta (109/L)

137 (79–221)

71 (44–136)

151 (94–232)

0.013

Procalcitonin (ng/mL)

1.13 (0.28–4.89)

1.56 (0.41–13.99)

1.06 (0.28–4.69)

0.490

Blood lactate (mmol/L)

1.89 (1.38–2.73)

1.81 (1.36–2.23)

1.92 (1.40–2.81)

0.511

PT (s)

15.7 (15.0–17.6)

16.3 (15.4–17.8)

15.7 (14.9–17.3)

0.569

APTT (s)

42.5 (37.9–51.4)

45.5 (37.9–65.5)

42.2 (37.9–49.1)

0.188

Cardiac troponins (ng/mL)

0.06 (0.03–0.41)

0.10 (0.05–0.14)

0.06 (0.03–1.10)

0.704

NT-proBNP (pg/mL)

1738 (528–4284)

2522 (660–7487)

1718 (453–3054)

0.167

AST (U/L)

48.7 (33.1–81.9)

43.9 (38.0–62.0)

48.7 (32.7–89.0)

0.448

ALT (U/L)

26.7 (15.4–56.6)

25.8 (18.9–43.4)

27.7 (15.4–58.5)

0.352

Albumin (g/L)

31.4 (27.8–34.7)

32.3 (27.8–34.9)

31.1 (27.8–34.5)

0.918

T-BIL (μmol/L)

15.2 (9.5–25.0)

21.1 (9.5–26.5)

15.0 (9.7–20.5)

0.150

D-BIL (μmol/L)

5.0 (2.5–11.5)

8.6 (2.1–11.3)

4.8 (2.7–12.2)

0.388

Scr (μmol/L)

102 (72–177)

173 (77–270)

99 (72–163)

0.184

BUN (mmol/L)

11.0 (6.7–17.8)

13.0 (7.2–34.4)

10.8 (6.6–17.3)

0.194

T lymphocytes (%)

66.5 (57.1–76.8)

64.6 (58.3–72.1)

67.6 (58.2–73.5)

0.885

Th lymphocytes (%)

34.9 (25.2–46.1)

35.6 (27.0–37.3)

32.5 (25.3–41.5)

0.391

Ts lymphocytes (%)

24.5 (17.1–33.2)

23.1 (19.6–30.5)

28.8 (19.6–33.2)

0.287

Th/Ts

1.22 (0.97–2.24)

1.36 (1.01–1.58)

1.15 (0.96–1.78)

0.394

B lymphocytes (%)

17.7 (7.6–26.5)

13.1 (1.1–32.4)

17.5 (12.9–24.9)

0.606

NK cellsa (%)

9.6 (6.0–15.9)

4.7 (2.6–7.4)

11.9 (7.0–15.7)

0.030

IL-2 (pg/mL)

1.00 (0.60–1.36)

0.97 (0.52–1.34)

1.00 (0.67–1.31)

0.872

IL-4 (pg/mL)

1.41 (0.84–2.43)

0.93 (0.74–1.78)

1.51 (0.91–2.23)

0.439

IL-6 (pg/mL)

55.86 (12.80–181.87)

88.42 (32.83–153.56)

51.95 (12.77–168.13)

0.651

IL-10 (pg/mL)

6.03 (3.67–11.61)

7.00 (3.26–17.83)

5.31 (3.77–11.28)

0.849

TNF-α (pg/mL)

1.01 (0.74–1.65)

0.94 (0.59–1.30)

1.06 (0.76–1.65)

0.350

INF-γ (pg/mL)

1.38 (0.69–3.68)

1.21 (0.64–6.01)

1.41 (0.74–3.51)

0.895

  1. CMV: Cytomegalovirus; P/F: PaO2/FiO2; PT: prothrombin time; APTT: activated partial thromboplastin time; NT-proBNP: N-terminus Precursor of B-type Natriuretic Peptide; AST: aspartate aminotransferase; ALT: alanine transaminase; T-BIL: total bilirubin; D-BIL: direct bilirubin; Scr: serum creatinine; BUN: serum urea nitrogen; Th: T-helper lymphocytes; Ts: T-suppressor Lymphocytes; NK: natural killer; IL: Interleukin; TNF: Tumor necrosis factor; INF: Interferon
  2. aP < 0.05; Continuous variables were expressed as Median (IQRs); Bold font indicates the difference was statistically significant