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Table 4 Clinical characteristic AK patients with respect to the Acanthamoeba genotype and its species

From: Assessment of genotypes, endosymbionts and clinical characteristics of Acanthamoeba recovered from ocular infection

S.N

Sample

ID

Patients age (years), gender, occupation

History of Ocular trauma, CL (yes/no)

Stromal

infiltrate

Hypopyon

Major symptoms

Size of epithelial defect (vxh) mm

Medical

treatment

duration

(days)

Surgical

treatment

Healing

of ulcer

Species, genotype

Presence or absence of endosymbionts

1

L-552/20

33, M, Farmer

NK, no

Yes

No

Pain, redness

0

38

No

Healed

A. culbertsoni, T4B

None detected

2

L-579/20

25, M, Student

NK, no

Yes

Yes

Pain, FB sensation, watering, redness

4 × 4.5

420

TPK, TABCL

Improved,

s/p TPK

A. polyphaga, T4B

Bacteria

3

L-604/20

8, F, Student

NK, no

Yes

No

Pain, watering, redness, decrease vision

6 × 6

5

No

Improved

Acanthamoeba spp.,

T4B

Bacteria

4

L-1133/20

32, F, Mason

NK, no

Yes

Yes

Pain, watering, decrease vision

4.5 × 4.5

23

No

Non-healing

A. culbertsoni, T4B

Bacteria

5

L-1137/20

56, M, Farmer

Ocular injury, no

Yes

Yes

Pain, redness, decrease vision

5.5 × 7

100

TPK,

TABCL,

AMG

Improved

A. triangularis, T4F

Bacteria

6

L-1257/20

43, M, Business

NK, no

No

No

Pain, redness

NK

240

 

Improved,

s/p TPK

A. culbertsoni, T4B

None detected

7

L-1326/20

37, M, Business

NK, yes

Yes

No

Decrease vision, redness, whitish spot on cornea

NK

15

No

Improved

A. polyphaga, T4B

Bacteria

8

L-1765/20

14, F, Student

NK, no

No

Yes

Pain, watering, redness, whitish spot on cornea

NK

90

TPK

Improved,

s/p TPK

Acanthamoeba spp.,

T4A

None detected

9

L-2391/20

20, F, Student

NK, no

Yes

Yes

Watering, decrease vision, redness, whitish spot on cornea

7.2 × 9

67

RB-PDAT

Improved

A. healyi, T12

Bacteria

10

L-2429/20

25, M, Farmer

Chemical injury, no

No

No

Pain, redness, decrease vision

Perforated cornea

11

No

Improved

A. triangularis, T4B

Fungi

11

L-2482/20

42, M, Farmer

Ocular injury, no

Yes

Yes

Redness, decrease vision

Tissue adhesive was in place

29

Tarso, AMG,

TPK

(post-injury)

Non-healing

A. culbertsoni, T4B

Bacteria

12

L-2483/20

22, F, Student

NK, yes

Yes

No

Watering, redness, decrease vision

NK

30

TPK

Improved

A. culbertsoni, T4B

Bacteria

13

L-2487/20

72, M, Farmer

Ocular

injury, no

Yes

No

Pain, FB sensation, watering, redness

6 × 6

60

Evisceration

Worsened

A. culbertsoni, T4B

None detected

  1. M male, F female, CL contact lens, FB foreign body, NK not known/reported, TPK therapeutic penetrating keratoplasty, TABCL Cyanoacrylate tissue adhesive with BCL (bandage contact lens), AMG amniotic membrane graft, s/p status post, RB-PDAT Rose Bengal-photodynamic antimicrobial therapy