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Table 1 Model parameters. The first five parameters: proportion of high activity group, ratio of number of partnerships of high-activity group to the low-activity group, transmission risk of receptive acts, HIV testing rate per year and ART initiation rate per year, all used ranges in the calibration. The latter parameters used point estimates based on the sources

From: Modeling the potential impact of pre-exposure prophylaxis for HIV among men who have sex with men in Cameroon

Model

 

Range or value

Final model

 

Parameter

Symbol

Yaounde

Douala

Yaounde

Douala

Source

Proportion of high activity group

NH/(NH + NL)

[0.073, 0.196]

[0.124, 0.217]

0.178

0.193

[25, 29]

Ratio of number of partnerships high-activity group to low-activity group

CH/CL

[3.977, 6.792]

[4.805, 6.636]

6.31

6.16

[25, 29]

Condom use proportion,

pc11

[0.418, 0.707]

[0.467, 0.714]

0.451

0.508

[29]

negative-negative

HIV testing rate (per year)

\(\psi\)

[0.61, 0.69]

[0.65, 0.67]

0.649

0.661

[29]

ART initiation rate (per year)

k

[0.07, 0.51]

[0.08, 0.79]

0.241

0.532

[29]

ART dropout rate

kD

0.15

0.15

0.15

0.15

[29]

Proportion of sex acts insertive

α

0.5

0.5

0.5

0.5

[29]

Proportion of sex acts receptive

1-α

0.5

0.5

0.5

0.5

[29]

Number of concurrent partners, low activity group (per person per year)

CL

4

5

4

5

[29]

Condom use odds ratio,

OR_pc12

2.203

2.203

2.203

2.203

[29]

positive–negative

Proportion of viral suppression among ART users

TART

0.89

0.91

0.89

0.91

[29]

Transmission risk, insertive acts

ßi

0.0011

0.0011

0.0011

0.0011

[46]

Transmission risk, receptive acts

ßr

0.0073

0.0073

0.0073

0.0073

[46]

Annual number of sex acts per partnership

Nsa

20

16

20

16

[29]

Condom efficacy

dcondom

80%

80%

80%

80%

[47]

PrEP efficacy

Ω

44%

44%

44%

44%

[18]

Entry/exit rate

m

0.026

0.026

0.026

0.026

[29, 48]

Exit rate due to HIV mortality

mHIV

0.076

0.076

0.076

0.076

[49]

Exit rate due to HIV mortality while on ART

mHIV_T

0.031

0.031

0.031

0.031

[49]