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Table 3 The factors associated with drug resistance among the participants

From: HIV-1 pretreatment drug resistance and genetic transmission network in the southwest border region of China

Variable

Number

PDR N (%)

Univariate analysis

Multivariate analysis

OR (95%CI)

p

aOR (95%CI)

p

Total

295

32 (10.8)

    

Sex

      

 Male

202

20 (9.9)

1.00

  

 Female

93

12 (12.9)

1.35 (0.63–2.89)

0.442

  

Age

   

0.489

  

 15–29

60

5 (8.3)

1.00

  

 30–39

99

12 (12.1)

1.52 (0.51–4.54)

0.456

  

 40–49

77

6 (7.8)

0.93 (0.27–3.21)

0.908

  

 ≥ 50

59

9 (15.3)

1.98 (0.62–6.31)

0.248

  

Ethnicity

      

 Others

179

17 (9.5)

1.00

  

 Han

116

15 (12.9)

1.42 (0.68–2.96)

0.356

  

Registered residence

   

0.775

  

 Pu’er

253

26 (10.3)

1.00

  

 Other cities in Yunnan

17

3 (17.6)

1.87 (0.50–6.94)

0.349

  

 Other provinces

21

3 (14.3)

1.46 (0.40–5.28)

0.568

  

 Foreign countries

4

0

0.00

0.999

  

Marital status

   

0.486

  

 Unmarried

131

11 (8.4)

1.00

  

 Married

109

14 (12.8)

1.61 (0.70–3.70)

0.265

  

 Divorced/widowed

55

7 (12.7)

1.59 (0.58–4.35)

0.365

  

Education

   

0.931

  

 Illiteracy

37

3 (8.1)

1.00

  

 Primary school

123

13 (10.6)

1.34 (0.36–4.98)

0.663

  

 Junior middle school

100

12 (12.0)

1.55 (0.41–5.82)

0.52

  

 Senior middle school and above

35

4 (11.4)

1.46 (0.30–7.06)

0.636

  

Occupation

      

 Farmers

231

21 (9.1)

1.00

1.00

 Others

64

11 (17.2)

2.08 (0.94–4.57)

0.070

1.86 (0.80–4.31)

0.149

Infection route

   

0.772

  

 Injected drug use

27

2 (7.4)

1.00

  

 Heterosexual contact

247

30 (12.1)

1.73 (0.39–7.67)

0.472

  

 Homosexual contact

21

0

0

0.998

  

Strain type

   

0.057

 

0.074

 CRF08_BC

183

14 (7.7)

1.00

1.00

 CRF07_BC

46

6 (13.0)

1.81 (0.66–5.00)

0.252

1.61 (0.56–4.63)

0.382

 CRF01_AE

52

11 (21.2)

3.24 (1.37–7.66)

0.007

3.14 (1.29–7.62)

0.012

 Others

14

1 (7.1)

0.93 (0.11–7.63)

0.945

0.74 (0.09–6.40)

0.781

ART exposure

      

 Naive

269

27 (10.0)

1.00

1.00

 Exposed

26

5 (19.2)

2.13 (0.74–6.12)

0.158

2.53 (0.85–7.54)

0.095

Baseline CD4 (cells/µl)

   

0.486

  

 < 350

171

17 (9.9)

1.00

  

 ≥ 350

102

14 (13.7)

1.61 (0.70–3.70)

0.265

  

 Unknown

22

1 (4.5)

1.59 (0.58–4.35)

0.365