Table 2 The drug resistance mutations detected among the participants
DRM | CRF01_AE (%) | CRF07_BC (%) | CRF08_BC (%) | others (%) | Total (%) |
|---|---|---|---|---|---|
Total | 52 | 46 | 183 | 14 | 295 |
NNRTI | |||||
V179D | 0 | 2 (4.3) | 37 (20.2) | 2 (14.3) | 41 (13.9) |
E138A | 0 | 0 | 16 (8.7) | 1 (7.1) | 17 (5.8) |
V106I | 4 (7.7) | 1 (2.2) | 8 (4.4) | 1 (7.1) | 14 (4.7) |
K103N | 6 (11.5) | 3 (6.5) | 5 (2.7) | 0 | 14 (4.7) |
V179E | 2 (3.8) | 2 (4.3) | 8 (4.4) | 2 (14.3) | 14 (4.7) |
V179T | 8 (15.4) | 0 | 3 (1.6) | 0 | 11 (3.7) |
P225H | 2 (3.8) | 1 (2.2) | 0 | 0 | 3 (1.0) |
E138G | 1 (1.9) | 0 | 1 (0.5) | 1 (7.1) | 3 (1.0) |
A98G | 0 | 0 | 2 (1.1) | 0 | 2 (0.7) |
V179DE | 0 | 1 (2.2) | 1 (0.5) | 0 | 2 (0.7) |
E138Q | 0 | 0 | 1 (0.5) | 0 | 1 (0.3) |
G190A | 1 (1.9) | 0 | 0 | 0 | 1 (0.3) |
K101E | 1 (1.9) | 0 | 0 | 0 | 1 (0.3) |
V106M | 0 | 1 (2.2) | 0 | 0 | 1 (0.3) |
V179EK | 0 | 0 | 0 | 1 (7.1) | 1 (0.3) |
V179IT | 1 (1.9) | 0 | 0 | 0 | 1 (0.3) |
V179DE | 0 | 0 | 1 (0.5) | 0 | 1 (0.3) |
V179DIN | 0 | 0 | 1 (0.5) | 0 | 1 (0.3) |
V108I | 1 (1.9) | 0 | 0 | 0 | 1 (0.3) |
Y181C | 1 (1.9) | 0 | 0 | 0 | 1 (0.3) |
NRTI | |||||
A62V | 0 | 0 | 1 (0.5) | 0 | 1 (0.3) |
M41L | 0 | 0 | 1 (0.5) | 0 | 1 (0.3) |
T215I | 0 | 1 (2.2) | 0 | 0 | 1 (0.3) |
T69G | 1 (1.9) | 0 | 0 | 0 | 1 (0.3) |
M184I | 0 | 0 | 1 (0.5) | 0 | 1 (0.3) |
PI accessory | |||||
I47R | 1 (1.9) | 0 | 0 | 0 | 1 (0.3) |
I47T | 1 (1.9) | 0 | 0 | 0 | 1 (0.3) |
I47K | 1 (1.9) | 0 | 0 | 0 | 1 (0.3) |
K43T | 0 | 1 (2.2) | 0 | 0 | 1 (0.3) |
L10F | 1 (1.9) | 0 | 0 | 0 | 1 (0.3) |
L33F | 2 (3.8) | 0 | 0 | 0 | 2 (0.7) |
M46T | 0 | 0 | 1 (0.5) | 0 | 1 (0.3) |
Q58E | 0 | 1 (2.2) | 1 (0.5) | 0 | 2 (0.7) |
G48R | 0 | 0 | 1 (0.5) | 0 | 1 (0.3) |
G73S | 0 | 0 | 1 (0.5) | 0 | 1 (0.3) |
PI | |||||
I50V | 0 | 0 | 1 (0.5) | 0 | 1 (0.3) |