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Table 2 The patient characteristics of the prospective pre-COVID and COVID cohorts (n = 176)

From: The changing spectrum of microbial aetiology of respiratory tract infections in hospitalized patients before and during the COVID-19 pandemic

 

Pre-COVID cohort (n = 96)

COVID cohort (n = 80)

P-value

A: Baseline characteristics

 Demography

  Age

73 (59–80)

73 (58–79)

0.966

  Female

52 (54)

32 (40)

0.070

  Male

44 (46)

48 (60)

0.070

 Comorbidity

  Cardiovascular disease

48 (50)

42 (53)

0.764

  Diabetes mellitus

11 (11)

11 (14)

0.655

  Asthma/COPD

38 (40)

42 (53)

0.096

  Kidney disease

15 (16)

7 (9)

0.252

  Previous smoker

43 (45)

47 (59)

0.071

  Current smoker

20 (21)

16 (20)

> 0.999

 Vaccine status

  Influenza virusa

58 (60)

45 (56)

0.646

  Pneumococcal

28 (29)

34 (43)

0.081

B: Severity and outcome

 Severity scoreb

  CURB-65

1.0 (1.0–2.0)

1.0 (1.0–2.0)

0.296

  PSI

93 (71–111)c

91 (65–114)

0.864

 Outcome

  Length of stay (days)

3.1 (2.0–5.0)

3.1 (2.0–6.1)

0.747

  HDU or ICU admission

10 (10)

10 (13)

0.812

   Case fatality rate

     In-hospital

1 (1)

0 (0)

> 0.999

     30 days

1 (1)

1 (1)

> 0.999

     60 days

4 (4)

1 (1)

0.378

  1. Data shown as count (%) or median (IQR). P-values are calculated with Mann-Whitney’s U test and Fisher’s exact test, comparing the pre-COVID cohort with the COVID cohort
  2. COPD chronic obstructive pulmonary disease, CURB-65 confusion, urea, respiratory rate, blood pressure, age ≥ 65 years, PSI pneumonia severity index, HDU high dependency unit, ICU intensive care unit, IQR interquartile range, CAP community acquired pneumonia
  3. aVaccinated for influenza virus with the latest vaccine
  4. bOnly performed in for CAP patients
  5. cMissing for five CAP patients
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BMC Infectious Diseases

ISSN: 1471-2334

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