Table 1 Eligibility criteria for febrile and non-febrile subjects in Ghana, Madagascar and Ethiopia including recruitment healthcare facilities, site boundaries and demographic data
Country | Eligibility criteria | Site | Recruitment HCFs | Study/Catchment area | Population (2016) | ||
|---|---|---|---|---|---|---|---|
Ghana | FSs | Fever history of ≥ 3 days (72 h) OR temperature of ≥ 38.0 °C (tympanic)/ ≥ 37.5 °C (axillary) OR clinically suspected/diagnosed Salmonella infection AND malaria positivity (by RDT/microscopy) | Kintampo | Kintampo Municipal Hospital (Kintampo Health Research Centre) and Yezura Hospital | Municipalities Babatokuma, Busuama, Dawadawa No.2, Gulumpe, Kadelso, Kawampe/Kawompe, Kintampo, Kunsu, New Longoro/Mentukwa and Portor within Kintampo North District; municipalities Agyina/Ajina, Amoma, Ampoma, Anyima, Apesika, Chirehin, Jema, Krabonso, Nante, Ntankoro and Pramposo within Kintampo South District | Total | 202,525 |
Male | 102,629 | ||||||
Female | 99,896 | ||||||
< 15 yrs | 85,843 | ||||||
NFSs | Self-reported absence of fever history OR clinical indication of fever OR an infectious pathology within the past 28 days | ≥ 15 yrs | 116,683 | ||||
Madagascar | FSs | Fever history of ≥ 3 days (72 h) OR temperature of ≥ 38.0 °C (tympanic)/ ≥ 37.5 °C (axillary) OR clinically suspected/diagnosed Salmonella infection | Diego | CSB II Tanambao, Kabari Hospital, Tanambo Hospital | Diego or Antsiranana City | Total | 439,706 |
Male | 219,413 | ||||||
Female | 220,293 | ||||||
< 15 yrs | 181,599 | ||||||
≥ 15 yrs | 258,108 | ||||||
NFSs | Self-reported absence of fever history OR clinical indication of fever OR an infectious pathology within the past 28Â days | Mahajanga | CSB II Tanambao-Sotema, Centre Hopitalier Universitaire Mahavoky Atsimo, Centre Hospitalier Universitaire Zafisaona Gabriel | Mahajanga or Majunga City | Total | 562,300 | |
Male | 280,588 | ||||||
Female | 281,712 | ||||||
< 15 yrs | 232,230 | ||||||
≥ 15 yrs | 330,070 | ||||||
Ethiopia | FSs | Fever history of ≥ 3 days (72 h) OR temperature of ≥ 38.0 °C (tympanic)/ ≥ 37.5 °C (axillary) AND clinically suspected/diagnosed Salmonella infection OR unknown causes for febrile illness | Addis Ketema W7 | Millennium Health Center, St. Paul Hospital, Ras Desta Hospital | Municipalities 14, 29, 30 and 32 within District 7 of Addis Ababa | Total | 23,490 |
Male | 12,184 | ||||||
Female | 11,943 | ||||||
< 15 yrs | 10,044 | ||||||
≥ 15 yrs | 14,083 | ||||||
Addis Ketema W8 | Addis Raey Health Center, St. Paul Hospital, Ras Desta Hospital | Municipalities 2–6 and 9–12 within District 8 of Addis Ababa | Total | 36,227 | |||
Male | 18,295 | ||||||
Female | 17,932 | ||||||
< 15 yrs | 15,081 | ||||||
≥ 15 yrs | 21,146 | ||||||
Debre Birhan | Debre Birhan Health Center, Debre Birhan Referral Hospital | Municipalities 3–4, 6 and Chole within Debre Birhan Town of Northern Shoa Zone within Amhara Region | Total | 34,267 | |||
Male | 17,305 | ||||||
Female | 16,962 | ||||||
< 15 yrs | 14,266 | ||||||
≥ 15 yrs | 20,002 | ||||||
NFSs | Self-reported absence of fever history OR clinical indication of fever OR an infectious pathology within the past 28 days | Arba Minch | Arba Minch Health Center, Arba Minch Hospital | Municipalities Woze, Kulifo, Dil Fana, Menahiria, Gurba, Ediget Ber, Mehal Ketema, Wuha Minch within Arba Minch Town of Gamo Gofa Zone within Southern Nations, Nationalities and People’s Region | Total | 82,740 | |
Male | 41,783 | ||||||
Female | 40,956 | ||||||
< 15 yrs | 34,444 | ||||||
≥ 15 yrs | 48,295 | ||||||
Adama Zuria | Wenji Gefersa Health Center, Wenji Kuriftu Health Center, Adama Hospital Medical College | Municipalities Wenji Gefersa, Wenji Kuriftu, Didimtu, Bati Bora, Bati Germama, and Adulala Boku within Adama Zuria District of Eastern Shoa Zone within Oromia Region | Total | 18,694 | |||
Male | 9440 | ||||||
Female | 9253 | ||||||
< 15 yrs | 7782 | ||||||
≥ 15 yrs | 10,912 | ||||||
Wolayita Sodo | Sodo Town Health Center, Wolayita Sodo Zone Hospital | Municipalities Gebeya, Dil Betigil, Gido, Gola, Damota, Alem Damota, and Otona Kodo within Sodo District of Wolayita Zone within Southern Nations, Nationalities and People’s Region | Total | 67,619 | |||
Male | 34,148 | ||||||
Female | 33,471 | ||||||
< 15 yrs | 28,150 | ||||||
≥ 15 yrs | 39,469 | ||||||