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Fig. 2 | BMC Infectious Diseases

Fig. 2

From: Neutrophil CD64 index as a superior indicator for diagnosing, monitoring bacterial infection, and evaluating antibiotic therapy: a case control study

Fig. 2

Comparison of the nCD64 index among groups. AD The differential expression of CD64 on leucocyte surface in a representative bacteria-infected patient. A Nucleated cells were gated according to SSC and pan-leucocyte marker CD45 distribution; B Lymphocytes (blue, LYM gate), neutrophils (green, NEO gate), and monocytes (purple, MON gate) were gated from nucleated cells according to CD14 distribution; C The histogram of CD64 expression (MFI) on neutrophils, lymphocytes, and monocytes; D The formula of nCD64 index calculation. E The nCD64 levels are significantly higher in Respiratory Tract Infection Group and Bloodstream Infection Group than in controls or Negative Bacterial Culture Group, respectively (n = 36 for controls; n = 34 for Negative Bacterial Culture Group; n = 56 for Respiratory Tract Infection Group; n = 34 for Bloodstream Infection Group). NEO neutrophils, LYM lymphocytes, MON monocytes, SSC  side scatter, MFI mean fluorescence intensity, FITC fluorescein isothiocyanate, PE  phycoerythrin, PE-Cy5 phycoerythrin-cyanine5, nCD64 index neutrophil CD64 index. Data in B were analyzed by the one-way ANOVA with Bonferroni multiple comparison tests

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