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Table 8 Sensitivity analysis—model with original data vs model with duration of epidemic reduced by 20%

From: Model-based evaluation of the impact of prophylactic vaccination applied to Ebola epidemics in Sierra Leone and Democratic Republic of Congo

 

No reduction of days (original DRC)

 

No vaccination

H0G5

(Vaccine efficacy 30%)

H0G5

(Vaccine efficacy 90%)

Cumulative cases

(IQR; 95%CI)

2782 (700–4026; 54–9637)

1383 (302–2005; 48–5149)

1028 (228–1467; 47–3910)

Proportion of cases averted vs no vaccination (IQR; 95%CI)

 

50% (48–55%; 13–58%)

63% (61–67%; 13–70%)

 

20% reduction of days (DRC)

 

No vaccination

H0G5

(Vaccine efficacy 30%)

H0G5

(Vaccine efficacy 90%)

Cumulative cases

(IQR; 95%CI)

1711

(498–2449; 56–5823)

957

(248–1352; 48–3368)

757

(202–1092; 44–2631)

Proportion of cases averted vs no vaccination (IQR; 95%CI)

 

44%

(43–46%; 13–51%)

56%

(54–59%; 21–61%)

  1. DRC: Democratic Republic of the Congo; HCW: Healthcare workers; H0: 0% HCW vaccinated; G5: 5% Non-HCW vaccinated