Clinical features and risk factors of surgical site infections in HIV-negative patients with cryptococcal meningitis underwent ventriculoperitoneal shunt operations: a retrospective study

Table 2 Clinical symptoms, body temperature, and laboratory characteristics changes preoperative and postoperative

Variable	Preoperative	Postoperative	P value
Body temperature (°C)^a	37.00 ± 0.80	37.30 ± 0.90	< 0.001^***
Dizziness or headache^b	159 (81.96%)	142 (73.20%)	0.002^**
Nausea or vomiting^b	96 (49.48%)	69 (35.57%)	0.001^**
Intracranial pressure (mmH₂O)^a	326.55 ± 83.96	168.99 ± 44.70	< 0.001^***
WBC of blood (× 10⁹/L)^c	8.68 ± 4.44	9.36 ± 5.90	< 0.001^***
CRP (mg/L)^a	10.04 ± 26.42	36.52 ± 48.67	< 0.001^***
PCT (mg/L)^a	0.09 ± 0.12	0.14 ± 0.25	0.006^**
WBC of CSF (× 10⁶/L)^a	60.00 ± 85.00	62.00 ± 96.00	0.630
Albumin of CSF (g/L)^c	0.67 ± 0.69	1.72 ± 1.57	< 0.001^***
Glucose of CSF (mmol/L)^c	1.73 ± 2.11	1.47 ± 1.96	0.009^**

Data was shown as frequency (relative frequency), mean ± standard deviation or median (quartile range)
CSF cerebrospinal fluid, WBC white blood cell, CRP C-reactive protein, PCT procalcitonin
^**Means that the variables were statistically significant with significance level of 0.01
^***Means that the variables were statistically significant with significance level of 0.001
^aPaired samples Wilcoxon signed-rank test, ^bMcNemar test, ^cPaired samples T test

ISSN: 1471-2334