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Table 7 Relationship between Helicobacter pylori infection and dyslipidaemia, heart dysfunction, overweight/obesity adjusting with potential confounders (socio-economic lifestyle and medical history parameters) assessed by multivariable linear regression analysis

From: Relationship between active Helicobacter pylori infection and risk factors of cardiovascular diseases, a cross-sectional hospital-based study in a Sub-Saharan setting

Variable

Univariate logistic regression

Multivariate logistic regression

OR (95% CI)

p value

Model 1

Model 2

Model 3

Model 4

OR (95% CI)

p value

OR (95% CI)

p value

OR (95% CI)

p value

OR (95% CI)

p value

Dyslipidemia

 Hyper total cholesterol

2.3324 (1.4935–3.6423)

0.0002*

2.5848 (1.6235–4.1155)

0.0001*

2.4100 (1.5324–3.7903)

0.0001*

2.3373 (1.4610–3.7391)

0.0004*

2.5944 (1.5766–4.2692)

0.0002*

 High LDL-C

2.3096 (1.4289–3.7331)

0.0006*

2.5793 (1.5560–4.2754)

0.0002*

2.3600 (1.4550–3.8280)

0.0005*

2.3612 (1.4412–3.8684)

0.0006*

2.6794 (1.5839–4.5328)

0.0002*

 Low HDL-C

1.3321 (0.8489–2.0902)

0.2123

1.2658 (0.7919–2.0234)

0.3247

1.3480 (0.8565–2.1216)

0.1969

1.4080 (0.8786–2.2563)

0.1550

1.4103 (0.8588–2.3160)

0.1743

 High TG

1.2620 (0.8129–1.9592)

0.2327

1.1407 (0.7249–1.7951)

0.5693

1.2714 (0.8154–1.9825)

0.2894

1.2431 (0.7885–1.9598)

0.3487

1.1116 (0.6918–1.7861)

0.6620

Heart dysfunction

 High DBP

1.3807 (0.7510–2.5384)

0.2991

1.3082 (0.7348–2.3291)

0.3614

1.4359 (0.7764–2.6554)

0.2488

1.4466 (0.7600–2.7534)

0.2609

1.6772 (0.8404–3.3474)

0.1424

 High SBP

0.8135 (0.4495–1.4723)

0.4952

0.8575 (0.4655–1.5796)

0.6218

0.8020 (0.4412–1.4578)

0.4692

0.9498 (0.4999–1.8047)

0.8751

0.9589 (0.4900–1.8764)

0.9024

 Hypertension

1.0060 (0.5270–1.9204)

0.9855

1.0781 (0.5527–2.1032)

0.8253

0.9874 (0.5151–1.8927)

0.9695

1.0980 (0.5540–2.1760)

0.7888

1.0866 (0.5292–2.2310)

0.8210

 High heart rate

1.4646 (0.7441–2.8829)

0.2694

1.3885 (0.6947–2.7753)

0.3529

1.4854 (0.7514–2.9366)

0.2551

1.4730 (0.7065–3.0708)

0.3015

1.3765 (0.6460–2.9330)

0.4077

BMI

 Overweigh/Obesity

1.0813 (0.6936–1.6859)

0.7300

1.1474 (0.7240–1.8185)

0.5585

1.1063 (0.7054–1.7349)

0.6601

1.1104 (0.6992–1.7635)

0.6571

1.1785 (0.7234–1.9201)

0.5095

  1. DBP: Diastolic blood pressure; SBP: Systolic blood pressure; N, n: Number, (95% CI): 95% confidence intervals; OR: Odd ratio. Bold value with *: Significant. Model 1: Adjusted with sociodemographic and economic factors (sex, gender and income level); Model 2: Adjusted with lifestyle factors (smoking, alcohol consumption, physical activity); Model 3: Adjusted with medical history (history of hypertension, diabetes mellitus, and obesity); Model 4: Adjusted for all the confounding factors (Sociodemographic and economic, lifestyle and medical history)