From: Excess hospitalizations and mortality associated with seasonal influenza in Portugal, 2008–2018
Variable | Age groups (in years) | With comorbidities | Without comorbidities | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
0–4 | 5–18 | 19–49 | 50–64 | 65–74 | ≥ 75 | ≥ 65 | All ages | < 65 | ≥ 65 | < 65 | ≥ 65 | |
Share of hospitalizations (%) | ||||||||||||
9-year meana | 15.7 | 5.2 | 15.3 | 17.7 | 14.6 | 31.6 | 46.2 | 100.0 | 24.9 | 40.6 | 28.9 | 5.5 |
3-year meanb | 12.8 | 4.2 | 10.7 | 17.0 | 16.0 | 39.2 | 55.2 | 100.0 | 21.5 | 48.2 | 23.2 | 7.0 |
[Min; Max] | [8.8; 29.3] | [2.8; 15.5] | [7.6; 38.6] | [10.2; 24.7] | [5.3; 16.6] | [4.2; 50.7] | [9.4; 67.3] | [100; 100] | [15.8; 36.1] | [7.7; 59.6] | [15.2; 57.3] | [1.7; 8.6] |
Influenza as primary diagnosis (%) | ||||||||||||
9-years meana | 73.6 | 72.7 | 63.5 | 62.5 | 60.2 | 64.6 | 63.2 | 65.2 | 58.6 | 61.2 | 74.2 | 77.9 |
3-year meanb | 74.5 | 76.3 | 65.6 | 65.1 | 64.3 | 68.2 | 67.1 | 67.9 | 61.9 | 65.2 | 75.5 | 79.6 |
[Min; Max] | [66.2; 86.3] | [62.8; 84.6] | [42.9; 84.3] | [36.7; 80.2] | [37.3; 74.7] | [42.1; 73] | [42.4; 73.9] | [52.6; 82.4] | [35.6; 79.1] | [33.9; 71.5] | [65.7; 85.8] | [62.1; 85.1] |
LoS (in days) | ||||||||||||
9-year meana | 6.1 | 6.0 | 10.2 | 13.2 | 12.6 | 11.8 | 12.0 | 10.7 | 12.4 | 12.4 | 7.1 | 9.5 |
3-year meanb | 6.0 | 5.7 | 10.8 | 12.1 | 12.5 | 12.2 | 12.3 | 11.0 | 11.8 | 12.7 | 7.2 | 9.4 |
[Min; Max]c | [4.4; 7] | [4.2; 7.3] | [4.9; 11.5] | [9.3; 18] | [9.6; 14.2] | [9.6; 12.5] | [10; 12.7] | [7.1; 11.4] | [8.7; 15.5] | [10.1; 13.1] | [4.8; 8] | [7.5; 13.4] |
In-hospital case fatality risk (%) | ||||||||||||
9-year meana | 0.2 | 0.9 | 3.4 | 6.2 | 7.4 | 10.5 | 9.5 | 6.1 | 5.3 | 9.9 | 1.3 | 6.8 |
3-year meanb | 0.1 | 1.5 | 4.1 | 5.6 | 7.5 | 10.4 | 9.5 | 6.7 | 5.7 | 9.9 | 1.1 | 7.0 |
[Min; Max]c | [0; 0.8] | [0; 2.2] | [0; 4.7] | [2; 9.1] | [0; 11.8] | [5.2; 12.5] | [3.4; 11.4] | [2.4; 7.8] | [1; 6.5] | [1.9; 11.2] | [0.4; 2.7] | [0; 15.8] |
Use of supplemental oxygen (%) | ||||||||||||
9-year meana | 34.3 | 18.4 | 38.4 | 45.4 | 44.2 | 49.1 | 47.5 | 42.2 | 44.1 | 47.9 | 31.9 | 45.2 |
3-year meanb | 36.7 | 16.1 | 36.8 | 45.8 | 43.9 | 47.8 | 46.7 | 42.9 | 43.6 | 46.5 | 33.3 | 47.6 |
[Min; Max]c | [17.8; 41.8] | [2.8; 30.8] | [6.8; 48.8] | [20.5; 54.6] | [36.7; 52.9] | [42.9; 60.8] | [44.4; 57.1] | [24.8; 49] | [22.2; 52.9] | [44.2; 57.5] | [10.9; 38.2] | [26.3; 63] |
Use of non-invasive mechanical ventilation (%) | ||||||||||||
9-year meana | 3.1 | 4.1 | 5.7 | 11.6 | 13.3 | 11.9 | 12.3 | 9.3 | 10.6 | 13.4 | 3.4 | 4.3 |
3-year meanb | 3.6 | 5.5 | 7.5 | 12.6 | 14.1 | 12.6 | 13.0 | 10.8 | 12.3 | 14.1 | 4.3 | 5.2 |
[Min; Max]c | [0.6; 5.1] | [0; 9] | [0; 9.8] | [4.1; 18.4] | [0; 16.1] | [1.1; 14.3] | [0.7; 14.3] | [1; 12.1] | [2.7; 13.7] | [0.8; 15.7] | [0.5; 5.2] | [0; 6.5] |
Use of invasive mechanical ventilation (%) | ||||||||||||
9-year meana | 2.4 | 4.3 | 12.3 | 17.4 | 13.9 | 6.6 | 8.9 | 9.7 | 15.8 | 9.5 | 5.6 | 4.5 |
3-year meanb | 2.3 | 6.2 | 12.9 | 15.5 | 13.2 | 6.5 | 8.5 | 9.3 | 15.8 | 9.2 | 5.0 | 3.5 |
[Min; Max] | [0.9; 4.9] | [0; 9.1] | [0; 16.4] | [2.3; 24.9] | [5.5; 19.8] | [1.1; 9.8] | [3.5; 14.1] | [1.8; 14.3] | [3.2; 20] | [4.2; 16] | [0; 10.1] | [0; 27.3] |
Discharged to other healthcare serviced (%) | ||||||||||||
9-year meana | 2.2 | 3.4 | 6.3 | 7.7 | 5.6 | 4.5 | 4.8 | 5.1 | 6.6 | 5.0 | 4.2 | 3.8 |
3-year meanb | 2.1 | 3.6 | 7.0 | 7.5 | 4.8 | 4.3 | 4.4 | 4.9 | 6.6 | 4.7 | 4.5 | 2.6 |
[Min; Max]c | [0.8; 5.5] | [0; 5.8] | [0; 8.7] | [2; 12.3] | [2.5; 10.2] | [1.1; 7.1] | [3.5; 8.3] | [2.5; 6.8] | [1.6; 9] | [4; 7.1] | [1.6; 4.9] | [0; 22.7] |
Mean hospitalization cost per patiente (€) | ||||||||||||
9-year meana | 1278 | 1855 | 3753 | 5074 | 4096 | 2974 | 3327 | 3302 | 4714 | 3485 | 2024 | 2164 |
3-year meanb | 1174 | 2140 | 3805 | 4005 | 3885 | 3212 | 3174 | 3068 | 4411 | 3316 | 1614 | 2188 |
[Min; Max]c | [780; 2471] | [911; 2883] | [1441; 4647] | [3037;11030] | [2626; 6769] | [1621; 6154] | [2567; 5817] | [1791; 5994] | [2623; 8090] | [2718; 6514] | [917; 4228] | [1220; 4750] |