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Table 3 Summary of the characteristics of the hospitalizations for influenza by age group and existence of comorbidities in Portuguese public hospitals between 2008/2009 and 2017/2018

From: Excess hospitalizations and mortality associated with seasonal influenza in Portugal, 2008–2018

Variable

Age groups (in years)

With comorbidities

Without comorbidities

0–4

5–18

19–49

50–64

65–74

 ≥ 75

 ≥ 65

All ages

 < 65

 ≥ 65

 < 65

 ≥ 65

Share of hospitalizations (%)

 9-year meana

15.7

5.2

15.3

17.7

14.6

31.6

46.2

100.0

24.9

40.6

28.9

5.5

 3-year meanb

12.8

4.2

10.7

17.0

16.0

39.2

55.2

100.0

21.5

48.2

23.2

7.0

[Min; Max]

[8.8; 29.3]

[2.8; 15.5]

[7.6; 38.6]

[10.2; 24.7]

[5.3; 16.6]

[4.2; 50.7]

[9.4; 67.3]

[100; 100]

[15.8; 36.1]

[7.7; 59.6]

[15.2; 57.3]

[1.7; 8.6]

Influenza as primary diagnosis (%)

 9-years meana

73.6

72.7

63.5

62.5

60.2

64.6

63.2

65.2

58.6

61.2

74.2

77.9

 3-year meanb

74.5

76.3

65.6

65.1

64.3

68.2

67.1

67.9

61.9

65.2

75.5

79.6

[Min; Max]

[66.2; 86.3]

[62.8; 84.6]

[42.9; 84.3]

[36.7; 80.2]

[37.3; 74.7]

[42.1; 73]

[42.4; 73.9]

[52.6; 82.4]

[35.6; 79.1]

[33.9; 71.5]

[65.7; 85.8]

[62.1; 85.1]

LoS (in days)

 9-year meana

6.1

6.0

10.2

13.2

12.6

11.8

12.0

10.7

12.4

12.4

7.1

9.5

 3-year meanb

6.0

5.7

10.8

12.1

12.5

12.2

12.3

11.0

11.8

12.7

7.2

9.4

[Min; Max]c

[4.4; 7]

[4.2; 7.3]

[4.9; 11.5]

[9.3; 18]

[9.6; 14.2]

[9.6; 12.5]

[10; 12.7]

[7.1; 11.4]

[8.7; 15.5]

[10.1; 13.1]

[4.8; 8]

[7.5; 13.4]

In-hospital case fatality risk (%)

 9-year meana

0.2

0.9

3.4

6.2

7.4

10.5

9.5

6.1

5.3

9.9

1.3

6.8

3-year meanb

0.1

1.5

4.1

5.6

7.5

10.4

9.5

6.7

5.7

9.9

1.1

7.0

 [Min; Max]c

[0; 0.8]

[0; 2.2]

[0; 4.7]

[2; 9.1]

[0; 11.8]

[5.2; 12.5]

[3.4; 11.4]

[2.4; 7.8]

[1; 6.5]

[1.9; 11.2]

[0.4; 2.7]

[0; 15.8]

Use of supplemental oxygen (%)

 9-year meana

34.3

18.4

38.4

45.4

44.2

49.1

47.5

42.2

44.1

47.9

31.9

45.2

3-year meanb

36.7

16.1

36.8

45.8

43.9

47.8

46.7

42.9

43.6

46.5

33.3

47.6

 [Min; Max]c

[17.8; 41.8]

[2.8; 30.8]

[6.8; 48.8]

[20.5; 54.6]

[36.7; 52.9]

[42.9; 60.8]

[44.4; 57.1]

[24.8; 49]

[22.2; 52.9]

[44.2; 57.5]

[10.9; 38.2]

[26.3; 63]

Use of non-invasive mechanical ventilation (%)

 9-year meana

3.1

4.1

5.7

11.6

13.3

11.9

12.3

9.3

10.6

13.4

3.4

4.3

 3-year meanb

3.6

5.5

7.5

12.6

14.1

12.6

13.0

10.8

12.3

14.1

4.3

5.2

 [Min; Max]c

[0.6; 5.1]

[0; 9]

[0; 9.8]

[4.1; 18.4]

[0; 16.1]

[1.1; 14.3]

[0.7; 14.3]

[1; 12.1]

[2.7; 13.7]

[0.8; 15.7]

[0.5; 5.2]

[0; 6.5]

Use of invasive mechanical ventilation (%)

 9-year meana

2.4

4.3

12.3

17.4

13.9

6.6

8.9

9.7

15.8

9.5

5.6

4.5

 3-year meanb

2.3

6.2

12.9

15.5

13.2

6.5

8.5

9.3

15.8

9.2

5.0

3.5

 [Min; Max]

[0.9; 4.9]

[0; 9.1]

[0; 16.4]

[2.3; 24.9]

[5.5; 19.8]

[1.1; 9.8]

[3.5; 14.1]

[1.8; 14.3]

[3.2; 20]

[4.2; 16]

[0; 10.1]

[0; 27.3]

Discharged to other healthcare serviced (%)

 9-year meana

2.2

3.4

6.3

7.7

5.6

4.5

4.8

5.1

6.6

5.0

4.2

3.8

 3-year meanb

2.1

3.6

7.0

7.5

4.8

4.3

4.4

4.9

6.6

4.7

4.5

2.6

 [Min; Max]c

[0.8; 5.5]

[0; 5.8]

[0; 8.7]

[2; 12.3]

[2.5; 10.2]

[1.1; 7.1]

[3.5; 8.3]

[2.5; 6.8]

[1.6; 9]

[4; 7.1]

[1.6; 4.9]

[0; 22.7]

Mean hospitalization cost per patiente (€)

 9-year meana

1278

1855

3753

5074

4096

2974

3327

3302

4714

3485

2024

2164

 3-year meanb

1174

2140

3805

4005

3885

3212

3174

3068

4411

3316

1614

2188

 [Min; Max]c

[780; 2471]

[911; 2883]

[1441; 4647]

[3037;11030]

[2626; 6769]

[1621; 6154]

[2567; 5817]

[1791; 5994]

[2623; 8090]

[2718; 6514]

[917; 4228]

[1220; 4750]

  1. aIncludes the following seasons: 2008/2009, 2010/2011, 2011/2012, 2012/2013, 2013/2014, 2014/2015, 2015/2016, 2016/2017, 2017/2018. Excludes season 2009/10, since it was affected by the 2009 influenza A (H1N1) pandemic
  2. bIncludes the most recent seasons, namely 2015/2016, 2016/2017, 2017/2018
  3. cMinimum and maximum values observed throughout the analyzed seasons for each age group
  4. dDischarges to long-term hospital care, specialized care, post-hospital care, palliative care, transference to other institution with inpatient care or home care; e Includes > 1 influenza hospitalization/patient