Table 2 UPLC-MS detected metabolites that varied in PCOS fungal sinusitis with significant difference (corrected p < 0.05)

Phytosphingosine

318.300^a

− 0.53

↑

2.1E−02

HMDB0004610

Organonitrogen compounds

LysoPC(18:1(11Z))

544.3354^a

− 4.14

↑

9.9E−03

HMDB0010385

Glycerophospholipids

PE (22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:0)

776.5623^a

4.37

↑

1.1E−04

HMDB0009684

Glycerophospholipids

Tryptophanol

184.0728^a

− 3.29

↑

1.1E−05

HMDB0244977

Indoles and derivatives

N-hexadecanoylsphinganine-1-phosphocholine

703.57161^a

− 4.60

↑

1.1E−05

HMDB0062665

Sphingolipids

SM(d18:1/18:0)

813.6819^a

− 3.07

↑

3.8E−05

HMDB0062559

Sphingolipids

Lactosylceramide (d18:1/24:1(15Z))

994.7175^a

− 1.70

↑

1.5E−04

HMDB0004872

Sphingolipids

PC(O-16:0/18:2(9Z,12Z)

786.5988_a

− 2.43

↑

1.1E−02

HMDB0011151

Glycerophospholipids

PC(O-16:0/0:0)

963.7126^a

− 1.124

↑

1.4E−03

CSID142380

Glycerophospholipids

PC(DiMe(11,3)/MonoMe(11,3))

853.5844^a

2.06

↓

7.2E−07

HMDB0061395

Glycerophospholipids

Galabiosylceramide (d18:1/16:0)

862.6238^b

− 1.41

↑

4.3E−04

HMDB0004833

Sphingolipids

dl-Mevalonic acid

319.13698^a

2.14

↓

1.0E−05

HMDB0006024

Fatty acyls

Diacylglycerol

729.5670^a

0.83

↑

1.0E−03

HMDB0242173

Glycerolipids

Harman

365.1777^a

4.45

↓

6.0E−06

HMDB0035196

Alkaloids

PS(14:1(9Z)/14:0)

700.4173^a

1.91

↓

8.0E−07

HMDB0012341

Glycerophospholipids

PG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:2(11Z,14Z))

869.5322^a

2.26

↓

7.6E−08

HMDB0116601

Glycerophospholipids

PGP(i-13:0/a-25:0)

909.5572^a

− 2.33

↓

7.1E−06

HMDB0116553

Glycerophospholipids

CL(8:0/13:0/17:0/18:2(9Z,11Z))

1259.8071^a

1.70

↓

4.0E−04

HMDB0119867

Glycerophospholipids

N-lactoyl-Tryptophan

299.1006^a

1.34

↑

2.9E−04

HMDB0062178

Carboxylic acids and derivatives

Ganglioside GM3 (d18:0/12:0)

1099.6683^a

− 4.73

↓

2.1E−06

HMDB0011913

Glycosphingolipids

l-Phenylalanine

166.0863^a

0.25

↑

6.5E−03

HMDB0000159

Carboxylic acids and derivatives

PGP(18:3(9Z,12Z,15Z)/16:0)

823.4563^b

3.80

↓

4.7E−04

HMDB0013577

Glycerophospholipids

LysoPC(0:0/18:2(9Z,12Z))

542.3214^a

− 2.86

↑

1.2E−02

HMDB0061700

Glycerophospholipids

Tenuazonic acid

395.2179^a

0.58

↑

5.9E−13

HMDB0036074

Pyrrolines (Fungal toxins)

Farnesyl pyrophosphate

383.1399^a

4.17

↓

1.3E−03

HMDB0000961

Prenol lipids

1-Oleoylglycerophosphoinositol

599.3181^a

− 1.66

↓

7.7E−15

HMDB0061693

Glycerophospholipids