Table 4 Comparison of laboratory findings among the four clusters
| Â | Cluster 1 | Cluster 2 | Cluster 3 | Cluster 4 | p-value |
|---|---|---|---|---|---|
Young healthy | Middle aged | Middle aged obese | Elderly | ||
WBC, /μL | 4854.2 ± 141 | 5530.2 ± 146.4 | 5531.3 ± 110 | 5553.9 ± 118.8 | 0.0003 |
Lymphocyte, % | 28.9 ± 0.7 | 19.9 ± 0.8 | 22.9 ± 0.6 | 21.1 ± 0.6 | < 0.0001 |
Lymphocyte, /μL | 1317.6 ± 38.8 | 1146.1 ± 26 | 1105 ± 40.8 | 1048.8 ± 24.2 | < 0.0001 |
Hb, g/dL | 14.5 ± 0.1 | 14.2 ± 0.1 | 14.8 ± 0.1 | 12.9 ± 0.1 | < 0.0001 |
PLT, × 104/μL | 21.9 ± 0.5 | 19.8 ± 0.5 | 19.3 ± 0.4 | 19 ± 0.4 | < 0.0001 |
Alb, g/dL | 4.3 ± 0.03 | 3.8 ± 0.03 | 3.8 ± 0.02 | 3.5 ± 0.03 | < 0.0001 |
TB, mg/dL | 0.6 ± 0.03 | 0.7 ± 0.03 | 0.7 ± 0.02 | 0.6 ± 0.02 | 0.0104 |
ALP, U/L | 154.5 ± 8.4 | 163.5 ± 8.6 | 178.2 ± 6.5 | 188.3 ± 6.9 | 0.0091 |
γGTP, U/L | 41.5 ± 5.3 | 66.5 ± 5.5 | 92.3 ± 4.1 | 48.5 ± 4.4 | < 0.0001 |
AST, U/L | 26.6 ± 2 | 41.7 ± 2.1 | 45.2 ± 1.6 | 36 ± 1.7 | < 0.0001 |
ALT, U/L | 28.8 ± 2.1 | 33.9 ± 2.2 | 49.7 ± 1.6 | 26.6 ± 1.7 | < 0.0001 |
BUN, mg/dL | 10.8 ± 0.9 | 16.7 ± 0.9 | 15.9 ± 0.7 | 21.1 ± 0.7 | < 0.0001 |
Cr, mg/dL | 0.7 ± 0.1 | 1.3 ± 0.1 | 1.1 ± 0.1 | 1.2 ± 0.1 | 0.0006 |
LDH, U/L | 193.8 ± 5.9 | 267.7 ± 6.1 | 272.3 ± 4.6 | 266 ± 4.9 | < 0.0001 |
UA, mg/dL | 4.7 ± 0.1 | 4.6 ± 0.1 | 5.2 ± 0.1 | 4.9 ± 0.1 | < 0.0001 |
CK, U/L | 93.9 ± 31.7 | 226.4 ± 32.8 | 152.1 ± 24.3 | 154 ± 26.2 | 0.0375 |
Na, mEq/L | 140.1 ± 0.2 | 137.7 ± 0.2 | 137.8 ± 0.2 | 137.9 ± 0.2 | < 0.0001 |
K, mEq/L | 4 ± 0.03 | 4 ± 0.03 | 4 ± 0.02 | 4 ± 0.02 | 0.4417 |
Cl, mEq/L | 103.5 ± 0.2 | 101.1 ± 0.3 | 101 ± 0.2 | 101.9 ± 0.2 | < 0.0001 |
TroponinT, ng/mL | 0.1 ± 1 | 1.2 ± 1.1 | 0.6 ± 0.8 | 2.4 ± 0.9 | 0.2919 |
BNP, pg/mL | 7.5 ± 19.1 | 33.5 ± 15.7 | 31.4 ± 12.4 | 86.1 ± 13.8 | 0.0025 |
IgG, mg/dL | 1197.4 ± 25.4 | 1184 ± 27.3 | 1208.2 ± 18.7 | 1231.6 ± 21 | 0.5306 |
IgA, mg/dL | 231.9 ± 10.4 | 252.1 ± 11.4 | 287.2 ± 7.6 | 264.1 ± 8.5 | 0.0002 |
IgM, mg/dL | 108.5 ± 4.6 | 82.5 ± 5 | 87.5 ± 3.3 | 85 ± 3.8 | 0.0001 |
C3, mg/dL | 120.9 ± 4.1 | 123.4 ± 3.8 | 138.8 ± 2.5 | 111.7 ± 3.1 | < 0.0001 |
C4, mg/dL | 34.5 ± 1.9 | 39.9 ± 1.8 | 43.4 ± 1.2 | 34.7 ± 1.4 | < 0.0001 |
CH50, U/mL | 56.8 ± 5 | 73.2 ± 5.3 | 75.8 ± 3.2 | 63.8 ± 3.2 | 0.0053 |
Ferritin, ng/mL | 240.7 ± 33.4 | 533.3 ± 35.1 | 655.4 ± 25.8 | 412.7 ± 28.6 | < 0.0001 |
TG, mg/dL | 115.5 ± 10.8 | 114.6 ± 11.1 | 159.3 ± 7.6 | 108 ± 8.5 | < 0.0001 |
KL-6, U/mL | 199.3 ± 16.1 | 273.4 ± 16.7 | 307.1 ± 12.4 | 356.2 ± 13.3 | < 0.0001 |
HbA1c, % | 5.5 ± 0.1 | 6.3 ± 0.1 | 6.7 ± 0.1 | 6.3 ± 0.1 | < 0.0001 |
APTT, sec | 33.6 ± 0.6 | 34.5 ± 0.6 | 34.2 ± 0.4 | 36.1 ± 0.5 | 0.0019 |
PT-INR | 1 ± 0.01 | 1 ± 0.01 | 1 ± 0.01 | 1.1 ± 0.01 | 0.0061 |
Fibrinogen, mg/dL | 363.7 ± 9.7 | 514.9 ± 10.1 | 514.6 ± 7.2 | 475.8 ± 7.8 | < 0.0001 |
d-dimer, μg/mL | 0.8 ± 0.4 | 1.7 ± 0.4 | 1.5 ± 0.3 | 2.8 ± 0.3 | < 0.0001 |
Procalcitonin, ng/mL | 0.1 ± 0.1 | 0.3 ± 0.1 | 0.1 ± 0.1 | 0.3 ± 0.1 | 0.0835 |
CRP, mg/dL | 1.1 ± 0.3 | 5 ± 0.3 | 5 ± 0.2 | 4.7 ± 0.2 | < 0.0001 |