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Table 2 Baseline characteristics for each cluster

From: Clinical clustering with prognostic implications in Japanese COVID-19 patients: report from Japan COVID-19 Task Force, a nation-wide consortium to investigate COVID-19 host genetics

 

Cluster 1

Cluster 2

Cluster 3

Cluster 4

p-value

Young healthy

Middle aged

Middle aged obese

Elderly

n = 266

n = 245

n = 435

n = 376

Age, years

31.7 ± 0.6

61.1 ± 0.6

56.9 ± 0.5

76.1 ± 0.5

< 0.0001

Male, n (%)

135 (50.8)

180 (73.5)

364 (83.7)

181 (48.1)

< 0.0001

BMI, kg/m2

22.9 ± 0.2

22 ± 0.2

28.3 ± 0.2

22.3 ± 0.2

< 0.0001

Smoking history, n (%)

99 (37.2)

117 (47.8)

247 (56.8)

134 (35.6)

< 0.0001

Hypertension, n (%)

0 (0)

13 (5.3)

206 (47.4)

230 (61.2)

< 0.0001

Diabetes mellitus, n (%)

2 (0.8)

56 (22.9)

124 (28.5)

81 (21.5)

< 0.0001

Malignancy, n (%)

6 (2.3)

13 (5.3)

18 (4.1)

62 (16.5)

< 0.0001

COPD, n (%)

0 (0)

31 (12.7)

16 (3.7)

17 (4.5)

< 0.0001

Hyperuricemia, n (%)

4 (1.5)

4 (1.6)

98 (22.5)

28 (7.5)

< 0.0001

Cardiovascular disease, n (%)

1 (0.4)

1 (0.4)

47 (10.8)

65 (17.3)

< 0.0001

Chronic liver disease, n (%)

0 (0)

4 (1.6)

29 (6.7)

10 (2.7)

< 0.0001

Chronic kidney disease, n (%)

1 (0.4)

14 (5.7)

34 (7.8)

42 (11.2)

< 0.0001

  1. Data are shown as mean ± SD. Data were compared among groups using analysis of variance (ANOVA) and χ2 tests
  2. BMI, body mass index; COPD, chronic obstructive pulmonary disease