Table 5 Univariate and multivariate analysis of independent predictors for reversion to positive culture

Age

–

–

 < 35 years

5 (6.0)

–

–

–

–

 35–60 years

15 (15.0)

2.8 (1.0–8.0)

0.05

–

–

 ≥ 60 years

1 (5.6)

1.0 (0.1–8.5)

0.94

–

–

Type of drug resistance

–

–

 RR

1 (12.5)

–

–

–

–

 MDR

11 (7.7)

0.6 (0.1–5.2)

0.63

–

–

 XDR

9 (17.3)

1.5 (0.2–13.4)

0.73

–

–

History of TB treatment (new/previously treated)

2 (10.5)/19 (10.4)

1.0 (0.2–4.7)

0.99

–

–

Cavitary disease at baseline (yes/no)

18 (12.9)/3 (5.6)

0.4 (0.1–1.4)

0.14

Concomitant diabetes (yes/no)

3 (10.3)/18 (10.4)

1.0 (0.3–3.7)

0.99

Gender (male/female)

20 (13.5)/1 (1.9)

8.1 (1.1–62.1)

0.02

1.2 (0.4–4.1)

0.71

Treatment regimen (bedaquiline/non-bedaquiline)

3 (2.9)/18 (18.0)

0.1 (0.0–0.5)

< 0.001

0.1 (0.0–0.5)

0.002*

Regimen containing (BDQ+ Cfz) /Cfz

5 (5.4)/18 (36.0)

0.1(0.0–0.3)

< 0.001

0.1 (0. 0–0.4)

< 0.001*

Regimen containing (BDQ+ Lzd)/Lzd

5 (5.4)/7(30.4)

0.1 (0.0–0.5)

< 0.001

0.1(0.0–0.5)

0.001*

Regimen containing (BDQ+ FQs)/FQs

1(4.3)/19(24.4)

0.1 (0.0–1.1)

0.03

0.00 (–)

1.0

 Regimen containing (BDQ+Cs)/Cs

5 (6.5)/24 (26.4)

0.2 (0.1–0.5)

0.00

0.2(0.0–0.5)

0.001*

BDQ+injectable agents/injectable agents

4(7.4)/21(23.1)

0.3 (0.1–0.8)

0.016

0.1 (0.0–0.5)

0.006*