Table 2 Comparison of COVID-positive inpatients during predominantly-Delta period (June–November 2021) and during predominantly-Omicron period (December 2021–January 2022) by vaccination status
Vaccinated (at least 1 dose) | Not vaccinated | P* | |
|---|---|---|---|
Predominantly-Delta period | |||
N | 372 | 445 | |
Age, years | 67.1 ± 17.8 | 51.9 ± 17.4 | < 0.0001 |
Male sex | 209 (56.2%) | 228 (51.2%) | 0.16 |
Morbid obesity (BMI > 40) | 28 (7.9%) | 43 (9.8%) | 0.34 |
Charlson’s comorbidity index (CCI) | 6.17 ± 3.92 | 2.63 ± 2.99 | < 0.0001 |
Elixhauser’s comorbidity index (ECI) | 17.7 ± 13.1 | 8.22 ± 9.98 | < 0.0001 |
O2 saturation at admission ≤ 90% | 48 (12.9%) | 122 (27.4%) | < 0.0001 |
COVID-19 pneumonia | 248 (66.7%) | 379 (85.2%) | < 0.0001 |
Coagulopathy | 79 (21.2%) | 62 (13.9%) | 0.0059 |
LOS, days | 10.6 ± 13.4 | 9.35 ± 10.46 | 0.16 |
Admitted to ICU | 85 (22.8%) | 86 (19.3%) | 0.22 |
LOS in ICU, days | 7.95 ± 16.15 | 11.6 ± 17.4 | 0.0142 |
Mechanical ventilation | 46 (12.4%) | 60 (13.5%) | 0.64 |
Disposition: short-term care facility | 5 (1.3%) | 10 (2.2%) | 0.34 |
Disposition: long-term care facility | 65 (17.5%) | 30 (6.7%) | < 0.0001 |
Disposition: home | 246 (66.1%) | 354 (79.6%) | < 0.0001 |
Disposition: hospice | 26 (7.0%) | 10 (2.2%) | 0.0010 |
Expired | 30 (8.1%) | 41 (9.2%) | 0.56 |
Predominantly-Omicron period | |||
N | 881 | 572 | |
Age, years | 63.4 ± 19.3 | 56.8 ± 19.9 | < 0.0001 |
Male sex | 447 (50.7%) | 280 (49.0%) | 0.51 |
Morbid obesity (BMI > 40) | 68 (8.2%) | 53 (9.7%) | 0.32 |
Charlson’s comorbidity index (CCI) | 5.87 ± 4.01 | 3.84 ± 3.53 | < 0.0001 |
Elixhauser’s comorbidity index (ECI) | 16.1 ± 13.0 | 11.5 ± 12.1 | < 0.0001 |
O2 saturation at admission ≤ 90% | 115 (13.1%) | 133 (23.3%) | < 0.0001 |
COVID-19 pneumonia | 461 (52.3%) | 402 (70.3%) | < 0.0001 |
Coagulopathy | 130 (14.8%) | 72 (12.6%) | 0.24 |
LOS, days | 6.84 ± 5.52 | 7.79 ± 7.29 | 0.12 |
Admitted to ICU | 125 (14.2%) | 84 (14.7%) | 0.79 |
LOS in ICU, days | 4.79 ± 5.79 | 5.91 ± 7.35 | 0.26 |
Mechanical ventilation | 56 (6.4%) | 41 (7.2%) | 0.54 |
Disposition: short-term care facility | 10 (1.1%) | 2 (0.3%) | 0.11 |
Disposition: long-term care facility | 106 (12.0%) | 43 (7.5%) | 0.0056 |
Disposition: home | 659 (74.8%) | 468 (81.8%) | 0.0017 |
Disposition: hospice | 37 (4.2%) | 23 (4.0%) | 0.87 |
Expired | 69 (7.8%) | 36 (6.3%) | 0.27 |