The 2021 Dutch Working Party on Antibiotic Policy (SWAB) guidelines for empirical antibacterial therapy of sepsis in adults

Table 4 Suggested antibacterial therapy duration in patients with sepsis

Focus of sepsis	Suggested antibacterial treatment duration
Intra-abdominal infections, following effective source control and with favourable clinical response	Four days [111,112,113,114]
Cholangitis, following adequate drainage of the biliary tree	Up to 3 days [115]
VAP	Seven days [59]
HAP	Seven days
CVC infection with gram-negative pathogen, following removal of the CVC and with favourable clinical response	Up to 7 days [80]
CVC infection with CNS or enterococci, following removal of the CVC and with favourable clinical response	Zero to 7 days
No clear focus	Seven days [80]

ISSN: 1471-2334