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Table 1 Characteristics of the study population

From: Multi-marker approach using C-reactive protein, procalcitonin, neutrophil CD64 index for the prognosis of sepsis in intensive care unit: a retrospective cohort study

Variables

Overall (n = 349)

Survivor (n = 250)

Non-survivor (n = 99)

p

Demographics

 Age, years

66 (52–77)

65.5 (50–77)

66 (55–75)

0.527

 Males/females, n (%)

229/120 (65.6/34.4)

167/83 (66.8/33.2)

62/37 (62.6/37.4)

0.459

History

 Smoking, n (%)

94 (26.9)

69 (27.6)

25 (25.3)

0.656

 Drinking, n (%)

33 (9.5)

25 (10)

8 (8.1)

0.581

Comorbidities

 Hypertension, n (%)

172 (49.3)

126 (50.4)

46 (46.5)

0.507

 DM, n (%)

107 (30.7)

75 (30)

32 (32.3)

0.671

 CHD, n (%)

53 (15.2)

38 (15.2)

15 (15.2)

0.991

 CRF, n (%)

38 (10.9)

31 (12.4)

7 (7.1)

0.15

 CHF, n (%)

38 (10.9)

31 (12.4)

7 (7.1)

0.15

 COPD, n (%)

23 (6.6)

15 (6)

8 (8.1)

0.48

 CVD, n (%)

46 (13.2)

34 (13.6)

12 (12.1)

0.713

Site of infection

 Lower respiratory tract, n (%)

246 (70.5)

201 (80.4)

45 (45.5)

< 0.001

 Enterocoelia, n (%)

52 (14.9)

18 (7.2)

34 (34.3)

< 0.001

 Skin and soft tissue, n (%)

40 (11.5)

16 (6.4)

24 (24.2)

< 0.001

 Urinary system, n (%)

82 (23.5)

40 (16.0)

42 (42.4)

< 0.001

 Central nervous system, n (%)

24 (6.9)

12 (4.8)

12 (12.1)

0.015

 Unknown, n (%)

21 (6.0)

13 (5.2)

8 (8.1)

0.308

Blood parameters

 WBC (× 109/L), median [IQR]

13.06 (9.41–18.12)

12.82 (9.56–17.32)

14.33 (8.29–20.45)

0.446

 NEU (× 109/L), median [IQR]

11.57 (7.76–16.11)

11.12 (7.88–15.34)

12.84 (7.44–18.72)

0.186

 LYM (× 109/L), median [IQR]

0.92 (0.55–1.45)

1.01 (0.63–1.55)

0.68 (0.31–1.08)

< 0.001

 PLT (× 109/L), median [IQR]

197 (129–243)

206 (140–248.25)

160 (91–223)

0.001

 CRP(mg/dL), median [IQR]

75.1 (42.10–123.5)

61.7 (35.68–84.65)

149 (84.2–234.00)

< 0.001

 PCT(ng/mL), median [IQR]

4.77 (1.16–19.14)

2.70 (0.86–6.31)

28.87 (8.37–99.40)

< 0.001

 nCD64 index, median [IQR]

1.39 (0.61–3.10)

1.11 (0.45–1.62)

4.76 (2.57–7.30)

< 0.001

Severity scores

 APACHE II

20 (14.5–26)

16 (13–23)

30 (25–35)

< 0.001

 SOFA

8 (5–11)

6 (4–9)

13 (10–15)

< 0.001