Table 2 Clinical characteristics of four patients infected with putative Hv-CRKP
| Â | Patient 15 (H15) | Patient 36 (H36) | Patient 38 (H38) | Patient 42 (H42) |
|---|---|---|---|---|
Clinical characteristics | Â | Â | Â | Â |
 City | Huangshan | Hangzhou | Hangzhou | Huzhou |
 Ward | Department of Infectious Diseases | Department of Infectious Diseases | Anorectal Surgery, Intensive Care Unit, Department of Infectious Diseases | Department of Infectious Diseases |
 Underlying conditions | Septicemia, pneumonia, post-cholecystectomy, hepatic syst, cervical abscess | Dysfunction of liver, hepatic failure, Sjogren's syndrome, cholecystolithiasis, pulmonary infection, cervical erosion | General peritonitis, enterobrosis, intestinal obstruction, postoperative colon cancer, alcoholic liver disease, hypertension, diabetes mellitus, splenomegaly | Urinary tract infection, brain contusion, intracranial hemorrhage, epilepsia, hypertension |
Invasive procedures | Â | Â | Â | Â |
 Mechanical ventilation | No | Yes | Yes | No |
 Drainage catheters | No | Abdominal drainage tube | Abdominal drainage tube | No |
 Surgery | No | Yes | Yes | Yes |
 Date of admission | 2017-11-3 | 2017-5-17 | 2017-5-31 | 2017-8-2 |
 Date of specimen collection | 2017-11-17 | 2017-7-21 | 2017-7-20 | 2017-9-25 |
 Infection type | Pyogenic liver abscess | Abdominal infection | Peritonitis | Urinary tract infection, blood stream infection |
 Specimen type | Puncture fluid | Abscess | Drainage | Drainage |
 Prior treatment with broad spectrum antibiotics > 7 days within 2 months | Yes | Yes | No | No |
 Hospitalization within 90 days | No | No | No | No |
Clinical presentations | Â | Â | Â | Â |
 Temperature (Tmax) (℃) | 40.4 | 38.4 | 38.3 | 39.1 |
 Septic shock | No | Yes | Yes | No |
 WBC (109/L) | 13.6 | 9.6 | 26.3 | 21.4 |
 C-reactive protein (mg/L) | 108.7 | 203 | 60.38 | 124 |
 PaO2/FiO2 |  | 96.8 | 89% |  |
 ALT (IU/L) | 89 | 139 | 55 | 43 |
 LDH (U/L) | 215 | 270 | 284 |  |
 Cr (μmol/L) | 34 | 35 | 113 | 60 |
 Antimicrobials used after isolation of K. pneumoniae | Tigecycline, meropenem | Tigecycline, amikacin | Piperacillin/tazobactam, meropenem | Tigecycline, meropenem, polymyxin |
Clinical outcomes | Â | Â | Â | Â |
 Length of stay (days) | 14 | 64 | 50 | 53 |
 Days of mechanical ventilation | 0 | 9 | 15 | 0 |
 Duration of ICU stay (days) | 0 | 21 | 30 | 0 |
 Outcome | Survived | Died | Died | Died |