Fig. 5

Percentage of deaths averted assuming early or late treatment initiation. Percentage of deaths averted (compared to a baseline of no antiviral treatment) for A Kenya, B Mexico, C United States and D Belgium for early (within the first two days of symptoms, left column) or late (between days 2 and 5 of symptoms, right column) treatment. Here, we assumed an epidemic wave with parameters similar to those of the Omicron epidemic wave (transmissibility, vaccine effectiveness, and vaccination coverage). For each country, the colors represent four possible values of AVT (25, 50, 75 or 100% reduction in viral transmission in treated symptomatic individuals) and covering 10–100% of eligible symptomatic individuals