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Table 3 Distribution of mRDT-PfHRP-2 and semi-quantitative RDT-CRP tests results over non-malaria infections

From: Could combined rapid diagnostic testing for malaria and c-reactive protein be helpful for the diagnosis and management of febrile illnesses in children under-5 years of age in rural Burkina Faso?

Laboratory result (Infection type)

mRDT PfHRP2

(N = 396)

Negative mRDT–PfHRP2 and positive CRP test;

(N = 80)

Negative mRDT–PfHRP2 and negative CRP test;

(N = 44)

Positive

(n = 272)

Negative

(124)

CRP level

10–40 mg/L

CRP level

 > 40 mg/L

BIs (n = 49)

30 (61.2)

19 (38.8)

4 (8.2)

10 (20.4)

5 (10.2)

bBSI (n = 23), n (%)

12 (52.2)

11 (47.8)

3 (13.0)

7 (30.4)

1 (4.3)

 NTS (n = 15)

9 (60)

6 (40)

2 (13.3)

3 (20.0)

1 (6.7)

 TS (n = 2)

1 (50.0)

1 (50.0)

0 (0.0)

1 (50.0)

0 (0.0)

 E. coli (n = 3)

1 (33.3)

2 (66.7)

1 (33.3)

1(33.3)

0 (0.0)

 H. influenza (n = 1)

0 (0.0)

1 (100.0)

0 (0.0)

1 (100.0)

0 (0.0)

 E. agglomerans (n = 1)

0 (0.0)

1 (100.0)

0 (0.0)

1 (100.0)

0 (0.0)

 S. pneumonia (n = 1)

1 (100.0)

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

bGE (n = 25), n (%)

18 (72.0)

7 (28.0)

1 (4.0)

3 (12.0)

3 (12.0)

 NTS (n = 9)

8 (88.9)

1 (11.1)

1 (11.1)

0(0.0)

0 (0.0)

 EPEC (n = 16)

10 (62.5)

6 (37.5)

0 (0.0)

3 (18.75)

3 (18.75)

bUTI (n = 1), n (%)

0 (0.0)

1 (100.0)

0 (0.0)

0 (0.0)

1 (100.0)

 E. coli (n = 1)

0 (0.0)

1 (100.0)

0 (0.0)

0 (0.0)

1 (100.0)

nBIs (n = 74), n (%)

52 (70.3)

22 (29.7)

4 (5.4)

10 (13.5)

8 (10.8)

pGE (n = 70), n (%)

52 (74.3)

18 (25.7)

3 (4.3)

8 (11.4)

7 (10.0)

 Giardia intestinalis (n = 32)

23 (71.9)

9 (28.1)

1 (3.1)

5 (15.6)

3 (9.4)

 Entamoeba species (n = 20)

14 (70.0)

6 (30.0)

2 (10.0)

2 (10.0)

2 (10.0)

 Trichomonas intestinalis (n = 13)

11 (84.6)

2 (15.4)

0 (0.0)

1 (7.7)

1 (7.7)

 Endolimax nana (n = 4)

3 (75.0)

1 (25.0)

0 (0)

0 (0)

1 (25.0)

 Ascaris sp. (n = 1)

1 (100.0)

0 (0)

0 (0)

0 (0)

0 (0)

vGE (4), n (%)

0 (0.0)

4 (100.0)

1 (25.0)

2(50.0)

1 (25.0)

 Adenovirus species (n = 4)

0 (0.0)

4 (100.0)

1 (25.0)

2(50.0)

1 (25.0)

Unknown causes of fevera (n = 81), n (%)

0 (0.0)

81 (100)

23 (28.4)

28 (34.6)

30 (37.0)

  1. CRP: C-reactive protein; mRDT-PfHRP2:malaria rapid diagnostic test for Plasmodium falciparum-specific histidine-richprotein 2; BIs: bacterial infections; nBIs; non bacterial infections; bBSI: bacterial bloodstream infection; bGE: bacterial gastroenteritis; bUTI: bacterial urinary tract infection; pGE: parasitic gastroenteritis; vGE: viral gastroenteritis;: NTS: non-thypoid salmonella; TS: typhoid salmonella; EPEC: enteropathogenic Escherichia coli
  2. aChildren who have no infections (bacterial, non-bacterial, and malaria) diagnosed
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BMC Infectious Diseases

ISSN: 1471-2334

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