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Table 1 The Baseline clinical characteristics of eICU-CRD and MIMIC-IV patients

From: The relationship between hematocrit and serum albumin levels difference and mortality in elderly sepsis patients in intensive care units—a retrospective study based on two large database

  eICU-CRD MIMIC-IV
  Total (n = 16127) HCT-ALB < 6.7 (n = 9899) HCT-ALB ≥ 6.7 (n = 6238) P value Total (n = 3043) HCT-ALB < 6.7 (n = 1970) HCT-ALB ≥ 6.7 (n = 1073) P value
Age 76 (70,83) 76 (70,83) 76 (70,83) 0.532 75 (69,82) 75 (69, 81) 76 (70, 82) 0.048
 HCT (%) 30.8 (27.0,35.4) 28. (25.7,32.6) 34.3 (30.4,38.8)  < 0.001 32.0 (27.6,36.3) 29.7 (25.9, 33.5) 36.3 (32.9, 40.1)  < 0.001
 ALB (g/L) 27.0 (22.0,32.0) 29.0 (25.0,34.0) 22.0 (19.0,26.0)  < 0.001 28.0 (24.0,32.0) 30.0 (26.0, 34.0) 24.0 (21.0, 28.0)  < 0.001
 SOFA 7 (5,9) 7 (5,9) 7 (5,9)  < 0.001 7 (5,10) 7 (4, 10) 8 (5, 11)  < 0.001
Gender (%)     0.010     0.445
 Male 8607 (53.4) 5198 (52.6) 3409 (54.6)   1686 (55.4) 1102 (55.9) 584 (54.4)  
 Female 7520 (46.6) 4691 (47.4) 2829 (45.4)   1357 (44.6) 868 (44.1) 489 (45.6)  
BMI (%)      < 0.001     0.322
 Underweight 828 (5.1) 449 (4.5) 379 (6.1)   154 (5.1) 89 (4.5) 65 (6.1)  
 Normalweight 5110 (31.7) 3022 (30.6) 2088 (33.5)   965 (31.7) 628 (31.9) 337 (31.4)  
 Overweight 4520 (28.0) 2843 (28.7) 1677 (26.9)   876 (28.8) 573 (29.1) 303 (28.2)  
 Obese 5669 (35.2) 3575 (36.2) 2094 (33.6)   1048 (34.4) 680 (34.5) 368 (34.3)  
Ventilation (%)      < 0.001     0.001
 No 11,202 (69.5) 7061 (71.4) 4141 (66.4)   356 (11.7) 259 (13.1) 97 (9.0)  
 Yes 4925 (30.5) 2828 (28.6) 2097 (33.6)   2687 (88.3) 1711 (86.9) 976 (91.0)  
Dialysis (%)      < 0.001     0.712
 No 14,389 (89.7) 8656 (87.4) 5743 (92.1)   2724 (89.5) 1760 (89.3) 964 (89.8)  
 Yes 1738 (10.3) 1243 (12.6) 495 (7.9)   319 (10.5) 210 (10.7) 109 (10.2)  
Vasopressor (%)      < 0.001      < 0.001
 No 11,271 (69.9) 7205 (72.8) 4066 (65.2)   1218 (40.0) 859 (43.6) 359 (33.5)  
 Yes 4856 (30.1) 2684 (27.2) 2172 (34.8)   1825 (60.0) 1111 (56.4) 714 (66.5)  
Congestive heart Failure      < 0.001     0.040
 No 12,162 (75.4) 7310 (73.9) 4852 (77.8)   1712 (56.3) 1081 (54.9) 631 (58.8)  
 Yes 3965 (24.6) 2579 (26.1) 1386 (22.2)   1331 (43.7) 889 (45.1) 442 (41.2)  
Chronic pulmonary disease (%)     0.941     0.450
 No 12,804 (79.4) 7849 (79.4) 4955 (79.4)   2108 (69.3) 1355 (68.8) 753 (70.2)  
 Yes 3323 (20.6) 2040 (20.6) 1283 (20.6)   935 (30.7) 615 (31.2) 320 (29.8)  
Diabetes (%)      < 0.001     0.001
 No 13,409 (83.1) 8097 (81.9) 5312 (85.2)   1923 (63.2) 1204 (61.1) 719 (67.0)  
 Yes 2718 (16.9) 1792 (18.1) 926 (14.8)   1120 (36.8) 766 (38.9) 354 (33.0)  
Renal disease (%)      < 0.001      < 0.001
 No 14,669 (91.0) 8867 (89.7) 5802 (93.0)   2025 (66.5) 1240 (62.9) 785 (73.2)  
 Yes 1458 (9.0) 1022 (10.3) 436 (7.0)   1018 (33.5) 730 (37.1) 288 (26.8)  
Malignant cancer (%)     0.314     0.006
 No 12,699 (78.7) 7761 (78.5) 4938 (79.2)   2428 (79.8) 1542 (78.3) 886 (82.6)  
 Yes 3428 (21.3) 2128 (21.5) 1300 (20.8)   615 (20.2) 428 (21.7) 187 (17.4)  
Liver disease (%)      < 0.001     0.271
 No 15,352 (95.2) 9,461 (95.7) 5891 (94.4)   2586 (85.0) 1685 (85.5) 901 (84.0)  
 Yes 775 (4.8) 428 (4.3) 347 (5.6)   457 (15.0) 285 (14.5) 172 (16.0)  
Metastatic solid tumor (%)     0.069     0.247
 No 15,591 (96.7) 9,581 (96.9) 6010 (96.3)   2779 (91.3) 1790 (90.9) 989 (92.2)  
 Yes 536 (3.3) 308 (3.1) 228 (3.7)   264 (8.7) 180 (9.1) 84 (7.8)  
ICU mortality (%)      < 0.001      < 0.001
 No 13,899 (86.2) 8766 (88.6) 5133 (82.3)   2377 (78.1) 1601 (81.3) 776 (72.3)  
 Yes 2228 (13.8) 1123 (11.4) 1105 (17.7)   666 (21.9) 369 (18.7) 297 (27.7)  
Hospital mortality (%)      < 0.001      < 0.001
 No 12,585 (78.0) 8128 (82.2) 4457 (71.4)   2065 (67.9) 1391 (70.6) 674 (62.8)  
 Yes 3542 (22.0) 1761 (17.8) 1781 (28.6)   978 (32.1) 579 (29.4) 399 (37.2)  
  1. Continuous variables were expressed by median (interquartile), categorical variables were expressed by count (percentage)
  2. P values were calculated to compare difference between HCT-ALB groups for each dataset separately