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Table 3 Pairwise differences in calcium, phosphate, and hypophosphatemia at delivery for women in the P1084s substudy

From: Maternal and infant renal safety following tenofovir disoproxil fumarate exposure during pregnancy in a randomized control trial

  

TDF-ART

(N = 157)

ZDV-ART

(N = 165)

ZDV Alone

(N = 156)

Calcium (mg/dL)

N

141

143

137

 

Mean (sd)

8.72 (0.60)

8.77 (0.66)

8.78 (0.59)

 

Mean difference (95% CI) from TDF-ART

 

− 0.05 (− 0.20, 0.09)

− 0.06 (− 0.20, 0.08)

 

Mean difference (95% CI) from ZDV-ART

  

− 0.01 (− 0.16, 0.14)

Phosphate (mg/dL)

N

142

145

137

 

Mean (sd)

3.56 (0.60)

3.70 (0.58)

3.72 (0.61)

 

Mean difference (95% CI) from TDF-ART

 

− 0.14 (− 0.28, − 0.01)

− 0.17 (− 0.31, − 0.02)

 

Mean Difference (95% CI) from ZDV-ART

  

− 0.02 (− 0.16, 0.12)

Hypophosphatemia

No

136/142 (95.77)

143/145 (98.62)

135/137 (98.54)

 

Yes

6/142 (4.23)

2/145 (1.38)

2/137 (1.46)

 

Mean difference (95% CI) from TDF-ART

 

2.85 (− 0.97, 6.66)

2.77 (− 1.11, 6.64)

 

Mean difference (95% CI) from ZDV-ART

  

− 0.08 (− 2.84, 2.68)

  1. CrCl creatinine clearance, TDF tenofovir disoproxil fumarate, ZDV zidovudine, sd standard deviation, CI  confidence interval