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Table 3 Analysis for estimation of prevalence of MDR-TB in the new cases (n = 1046) and retreatment cases (n = 394)

From: Factors contributing to the high prevalence of multidrug-resistance/Rifampicin-resistance in patients with tuberculosis: an epidemiological cross sectional and qualitative study from Khabarovsk krai region of Russia

Variable

New cases (n = 1046)

Retreatment cases (n = 394)

Prevalence of MDR-TB (%)

AOR (95% CI)

p value

Prevalence of MDR-TB (%)

AOR (95% CI)

p value

Gender

      

 Female

36.4

1.25 (0.92 to 1.69)

0.157

65.6

1.24 (0.71 to 2.18)

0.441

 Male

34.1

1 (reference)

-

61.5

1 (reference)

–

Age, median years (range)

      

 ≥41 years

39.5

1.34 (0.99 to 1.81)

0.013

58.1

0.65 (0.38 to 1.09)

0.108

  < 41 years

30.0

1 (reference)

–

71.6

1 (reference)

–

Place of residence

      

 City

37.2

1.841 (1.32 to 2.57)

0.010

66.7

1.27 (0.72 to 2.26)

0.408

 Countryside

28.9

1 (reference)

-

63.6

1 (reference)

–

Social status (whole variable)

 

(–)

0.604

–

(–)

0.008

 Working

30.5

0,83 (0.58 to 1.19)

0.639

82.9

4,32 (0.58 to 1.19)

0.002

 Retired

24.8

0.66 (0.41 to 1.07)

0.042

45.9

0.66 (0.29 to 1.49)

0.042

 Student

30.8

0.75 (0.31 to 1.86)

0.879

100.0

–

0.999

 Not organized child

50.0

0.81 (0.09 to 6.81)

0.792

0.0

–

0.999

 In military service

100.0

–

0.999

0.0

–

0.999

 Not working

37.9

1 (reference)

–

64.2

1 (reference)

–

Living conditions (whole variable)

 

(–)

0.534

 

(–)

0.526

 Bed in designated facility

66.7

0.73 (0.12 to 4.37)

0.608

93.8

0.43 (0.05 to 3.68)

0.439

 Room in dormitory

22.2

0.64 (0.12 to 3.43)

0.978

100.0

–

0.999

 Room in separate apartment

0.0

–

0.999

100.0

–

0.999

 Separate house

37.3

1.379 (0.79 to 2.40)

0.595

60.6

0.78 (0.35 to 1.77)

0.560

 Separate apartment

33.7

0.98 (0.60 to 1.61)

0.28

59.1

0.52 (0.26 to 1.05)

0.070

 Homeless

37.2

1 (reference)

–

70.3

1 (reference)

–

Substances abuse (whole variable)

 

(–)

0.991

 

(–)

0.539

 Alcoholism

32.4

0.97 (0.47 to 1.99)

0.935

57.1

0.48 (0.13 to 1.73)

0.266

 Drug abuse

66.7

1.15 (0.09 to 14.14)

0.914

100.0

–

0.999

 No official records

34.8

1 (reference)

–

64.8

1 (reference)

–

Circumstance of TB discovery

      

 Discovered actively by healthcare facility

35.3

1.18 (0.88 to 1.57)

0.278

69.6

1.79 (1.06 to 3.05)

0.030

 Visit with symptoms to healthcare facility

34.0

(reference)

 

53.0

1 (reference)

 

Imprisonment history

      

 Being in detention or history of detention

82.6

11.9 (3.08 to 45.93)

 < 0.001

98.2

38.55 (3.65 to 407.42)

0.002

 No official history of detention

33.7

1 (reference)

 

59.2

1 (reference)

 

Cavitary disease

      

 Presence of cavities

40.1

1.95 (1.45 to 2.62)

 < 0.001

65.2

1.46 (0.87 to 2.44)

0.151

 No cavities

28.6

1 (reference)

 

63.8

1 (reference)

 

Disabilities

     

0.008

 Presence of disability

48.9

1.66 (0.87 to 3.15)

0.119

87.8

4.44 (1.47 to 13.38)

 

 No disability

34.1

1 (reference)

 

61.9

1 (reference)

 

TB localization:

 

(–)

0.494

 

(–)

0.999

 TB of lungs’ lymph system, pleural

38.5

1.69 (0.71 to 4.04)

0.235

0.0

–

 

 Non thoracic TB

0.0

–

0.999

0.0

–

 

 Pulmonary TB

35.0

1 (reference)

–

65.3

1 (reference)

 

HIV status

      

 Positive

46.8

1.67 (1.01 to 2.77)

0.047

67.5

1.48 (0.62 to 3.53)

0.378

 Negative

33.8

1 (reference)

 

64.3

1 (reference)

–

Previous therapy

      

 More than 180 days

–

–

–

61.4

0.92 (0.56 to 1.51)

0.732

 Less than 180 days

   

69.7

1 (reference)

 

Previous therapy outcome (whole variable)

     

0.061

 Not effective course

-

–

–

79.3

(–)

0.621

 Other

   

0.0

1.379 (0.79 to 2.40)

0.999

 Transferred

   

100.0

–

0.999

 Interrupted course

   

52.5

–

0.089

 Effective course

   

61.4

0.98 (0.60 to 1.61)

–

  1. HIV human immunodeficiency virus, TB tuberculosis, MDR/RR multidrug resistance/Rifampin resistance, AOR adjusted odds ratio