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Table 5 Changes in serum clearance and Glomerular filtration rate

From: Randomized controlled trial of the relative efficacy of high-dose intravenous ceftriaxone and oral cefixime combined with doxycycline for the treatment of Chlamydia trachomatis and Neisseria gonorrhoeae co-infection

  Doxycycline + ceftriaxone p value Doxycycline + cefixime p value p value
Clearance (mmol/L)
  At baseline 86.98 ± 40.26 0.661 80.32 ± 19.54 0.217 0.238
  At 8th day of treatment 84.57 ± 17.89 83.63 ± 15.44 0.752
GFR (mL/min/1.73 m2)
  At baseline 99.83 ± 30.03 0.176 100.22 ± 26.31 0.047 0.939
  At 8th day of treatment 95.33 ± 18.73 93.38 ± 20.92 0.586
Delta clearance − 2.28 ± 40.35   3.31 ± 21.28   0.331
Delta GFR − 4.54 ± 25.91   − 6.84 ± 26.7   0.626
  1. GFR glomerular filtration rate