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Table 2 Summary of findings (SOF) table for the primary outcomes

From: Systematic review and meta-analysis of ivermectin for treatment of COVID-19: evidence beyond the hype

Outcome

Study population

Relative effect

RR (95% CI)

Certainty of the evidence (GRADE)

Mortality

6048 patientsa (24 studies)

(RR = 0.76; 95%CI: 0.52–1.11)

  

Low

Mechanical ventilation requirement

5270 patientsb (153 studies)

(RR = 0.74; 95%CI: 0.48–1.16)

  

Low

  1. The body of evidence was graded as “low” due to serious risk of bias and imprecision
  2. GRADE Grading of Recommendations Assessment, Development and Evaluation, RR relative risk
  3. a6288 patients randomized, but 6048 included in the analysis
  4. b5405 patients randomized, but 5270 included in the analysis