Table 3 Reported pharmacodynamic targets for therapeutic drug monitoring of beta-lactams and ciprofloxacin in ICU patients (n = 21)
Beta-lactams | Â |
50% (f)T > MIC | 14% |
100% (f)T > MIC | 38% |
100% (f)T > 4xMIC | 43% |
100% (f)T > MIC ECOFF | 10% |
Do not know | 24% |
Ciprofloxacin | Â |
AUC/MIC > 120 | 29% |
(f)AUC/MIC > 100 | 14% |
(f)AUC/MIC > 90 | 5% |
Cmax/MIC > 10 | 10% |
fCmax/MIC > 8 | 5% |
Do not know | 57% |