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Table 2 Demographic characteristics and factors associated with drug resistance

From: Characterization of HIV-1 molecular epidemiology and transmitted drug-resistance in newly diagnosed HIV-infected patients in Sichuan, China

Variables

DR (%)a

Non-DR (%)a

OR (95% CI)

P-values

AOR (95% CI)

P-values

n = 138

n = 1159

Age (years)

 < 25b

6 (8.45)

65 (91.54)

1

   

 25~

13 (7.1)

170 (92.89)

1.42 (0.38–5.33)

0.608

  

 40~

13 (6.59)

184 (93.4)

0.99 (0.21–4.57)

0.987

  

 ≥ 50

40 (4.72)

806 (95.27)

0.80 (0.17–3.71)

0.776

  

Gender

 Maleb

51 (5.44)

885 (94.55)

1

   

 Female

21 (5.81)

340 (94.18)

1.05 (0.59–1.88)

0.863

  

Ethnicity

      

 Hanb

66 (5.44)

1146 (94.55)

1

   

 Yi

5 (7.57)

61 (92.42)

0.78 (0.17–3.52)

0.75

  

 Others

1 (5.26)

18 (94.73)

0.96 (0.09–6.49)

0.803

  

Marital status

 Unmarriedb

16 (7.01)

212 (92.98)

1

   

 Married or living

36 (4.95)

691 (95.04)

0.86 (0.38–1.95)

0.72

  

 With spouse

 Divorced/widowed

20 (5.93)

317 (94.06)

1.08 (0.45–2.60)

0.856

  

 Othersc

0 (0)

5 (100)

–

–

  

Education level

 Primary school and belowb

43 (5.51)

736 (94.48)

1

   

 Middle school

19 (5.65)

317 (94.34)

0.93 (0.48–1.79)

0.823

  

 High school or technical secondary school

5 (5.05)

94 (94.94)

0.61 (0.19–1.97)

0.41

  

 Junior college or above

5 (6.02)

78 (93.97)

0.73 (0.19–2.86)

0.656

  

Occupation

 Farmersb

39 (4.62)

804 (95.37)

1

   

 Unemployed

15 (8.37)

164 (91.62)

1.87 (0.91–3.82)

0.087

  

 Retired

1 (2.04)

48 (97.95)

0.51 (0.06–4.12)

0.532

  

 Others

17 (7.52)

209 (92.47)

1.58 (0.72–3.45)

0.25

  

Route of transmission

 HETb

60 (5.04)

1130 (94.95)

1

 

1

 

 MSM

6 (7.59)

73 (92.4)

1.34 (0.42–4.23)

0.622

1.91 (0.77–4.77)

0.163

 IDUs

1 (12.5)

7 (87.5)

4.63 (0.46–46.69)

0.193

4.86 (0.57–41.44)

0.148

 Others

5 (25)

15 (75)

7.55 (1.81–31.43)

0.005

8.13 (2.70–24.53)

< 0.001

Genotype

 CRF07_BCb

23 (3.42)

649 (96.57)

1

 

1

 

 CRF01_AE

14 (4.1)

327 (95.89)

1.39 (0.68–2.83)

0.362

1.29 (0.65–2.57)

0.465

 CRF08_BC

24 (20.86)

91 (79.13)

8.67 (4.43–16.96)

 < 0.001*

8.32 (4.38–15.80)

< 0.001*

 CRF85_BC

3 (4.54)

63 (95.45)

1.70 (0.47–6.15)

0.42

1.62 (0.47–5.61)

0.447

 B

1 (3.03)

32 (96.96)

0.72 (0.08–6.10)

0.759

0.88 (0.11–6.88)

0.901

 Others

7 (10)

63 (90)

3.73 (1.53–9.07)

0.004

3.43 (1.44–8.20)

0.005

  1. aDR indicates individuals with drug-resistant mutations, non-DR indicates individuals without drug-resistant mutations, and numbers in parentheses show the proportion for each variable
  2. bThe reference value of this subgroup of variables
  3. cSet as missing value
  4. *P values < 0.05 were considered statistically significant
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BMC Infectious Diseases

ISSN: 1471-2334

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