Author, country, year, reference | Age (years), sex | Symptoms | Underlying condition | Diagnostic method | Susceptibility MIC (µg/mL) | Other bacteria isolated | Treatment | Outcome |
---|---|---|---|---|---|---|---|---|
Lam et al. Hong Kong, 2011, [15] | 41, F | Headache, ptosis, diplopia | Subdural empyema, mycotic intracranial aneurysm | 16 S rRNA sequencing | ND | none | Coil embolization, craniectomy, VCM, CTRX, until dead | Died |
Leo and Bolger USA, 2014, [16] | 55, M | Headache, ophthalmoplegia, ptosis, fever | Septic cavernous sinus thrombosis, dental caries | 16 S rRNA sequencing | ND | none | Anticoagulation, steroids, VCM, CLDM, TAZ/PIPC (unknown duration) | Survived |
Jawad et al., UK, 2018, [17] | 29, M | Sore throat, fever, myalgia | Lemierre’s syndrome, septic pulmonary embolism, G6PD deficiency | MALDI-TOF MS, 16 S rRNA sequencing | ND | none | Anticoagulation, CVA/AMPC, CAM, TAZ/PIPC, MNZ, 6 weeks | Survived |
Oka et al. Japan, 2018, [18] | 70, F | Headache, fever | Clival osteomyelitis, cavernous sinus thrombosis, septic pulmonary embolism, odontogenic infection, HTN | unknown | ND | Fusobacterium nucleatum | SBT/ABPC, fluconazole, MEPM, MNZ (unknown duration) | Survived |
Genderini et al. Belgium, 2019, [19] | 70, M | Weight loss, fatigue, dysphagia, fever, cough, dyspnea | HSV-1 esophagitis, HIV-1 infection, periodontitis | MALDI-TOF MS, 16 S rRNA sequencing | CVA/AMPC 0.047 | Solobacterium moorei | CVA/AMPC (unknown duration) | Survived |
Present case | 75, M | Thigh pain | Femoral osteomyelitis, periodontitis, hyperuricemia, benign prostatic hyperplasia | MALDI-TOF MS, 16 S rRNA sequencing | ND | Parvimonas micra | SBT/ABPC, CVA/AMPC | Survived |