Table 5 Odds ratio (OR) with 95% CI for Non-vacA s1m1 genotypes and antibiotic resistance in H. pylori
Non-vacA s1m1 genotypes | Antibiotic resistance | Random-effects model | Heterogeneity | Publication bias | |||
|---|---|---|---|---|---|---|---|
OR (95% CI ) | p value | p value | I-squared | Egger’s p value | Begg’s p value | ||
vacA s1m2 | Clarithromycin | 0.13 (0.05–0.16) | 0.01 | 0.01 | 81.34 | 0.78 | 0.88 |
Metronidazole | 0.32 (0.12–0.81) | 0.01 | 0.01 | 92.01 | 0.50 | 0.20 | |
Amoxicillin | 0.11 (0.003-3.9) | 0.2 | 0.01 | 97.76 | 0.02 | 0.5 | |
Tetracycline | 0.05 (0.001-4.6) | 0.2 | 0.01 | 95.01 | 0.05 | 0.5 | |
Levofloxacin | 0.16 (0.02–1.36) | 0.09 | 0.01 | 93.48 | 0.04 | 0.5 | |
vacA s2m1 | Clarithromycin | 0.03 (0.01–0.09) | 0.01 | 0.01 | 0.00 | 0.05 | 0.7 |
Metronidazole | 0.07 (0.00-173.5) | 0.5 | 0.01 | 92.02 | NA | NA | |
Amoxicillin | 0.02 (0.00-1.34) | 0.06 | 0.9 | 0.00 | NA | NA | |
Tetracycline | 0.02 (0.00-1.34) | 0.06 | 0.9 | 0.00 | NA | NA | |
Levofloxacin | 0.02 (0.00-1.34) | 0.06 | 0.9 | 0.00 | NA | NA | |
vacA s2m2 | Clarithromycin | 0.07 (0.03–0.13) | 0.01 | 0.01 | 55.47 | 0.02 | 0.04 |
Metronidazole | 0.06 (0.02–0.15) | 0.01 | 0.01 | 84.67 | 0.52 | 0.50 | |
Amoxicillin | 0.04 (0.01–0.09) | 0.01 | 0.01 | 17.61 | 0.18 | 0.1 | |
Tetracycline | 0.03 (0.00-0.14) | 0.01 | 0.01 | 0.00 | 0.07 | 0.5 | |
Levofloxacin | 0.03 (0.01–0.12) | 0.01 | 0.01 | 21.26 | 0.78 | 0.5 | |
NA not available | |||||||