Table 1 Antibiotic susceptibility testing for Gram-positive isolates recovered from blood cultures
| Â | Â | S. aureus | CoNS & M. sciuri | ||||||
|---|---|---|---|---|---|---|---|---|---|
|  |  | MIC(µg/mL) | MIC(µg/mL) | ||||||
Antibiotic class | Antimicrobial | Range | MIC50 | MIC90 | Resistance breakpoint | % Resistant | Range | Resistance breakpoint | % Resistant |
Aminoglycosides | Amikacin | 4- > 32 | 4 | 4 |  > 8 | 4.0 | 4– > 32 |  > 8 | 18.2 |
Gentamicin | 0.5– > 8 | 0.5 |  > 4 |  > 1 | 18.0 | 0.5– > 4 |  > 1 | 40.9 | |
Tobramycin | 0.5– > 8 | 0.5 |  > 4 |  > 1 | 29.0 | 0.5– > 4 |  > 1 | 50.0 | |
Fluoroquinolones | Ciprofloxacin | 0.5– > 4 | 0.5 |  > 4 |  > 1 | 20.0 | 0.5– > 4 |  > 1 | 40.9 |
Levofloxacin | 0.5– > 4 | 0.5 |  > 4 |  > 1 | 15.0 | 0.5– > 4 |  > 1 | 40.9 | |
Glycopeptides | Vancoymcin | 1–2 | 1 | 1 |  > 2 | 0.0 | 1– > 8 |  > 4 | 2.3 |
MLS | Azithromycin | 1– > 8 | 4 |  > 8 |  > 2 | 53.0 | ND | ND | ND |
Oxazolidinones | Linezolide | 2–8 | 2 | 4 |  > 4 | 1.0 | 2– > 16 |  > 4 | 2.3 |
Ansamycins | Rifampicin | 0.03 | 0.03 | 0.03 |  > 0.5 | 0.0 | 0.03– > 0.25 |  > 0.5 | 13.6 |
Penicillins | Ampicillin | 2–128 | NA | NA | NA | NA | 2–64 | NA | NA |
Flucloxacillin | 0.5– > 8 | NA | NA | NA | NA | 1– > 8 | NA | NA | |
Oxacillin | 1– > 8 | 1 |  > 8 |  > 2 | 33 | 1– > 8 | 0.25 | 100 | |
Tetracyclines | Minocycline | 0.25– > 2 | 0.25 | 0.5 |  > 0.5 | 7.0 | 0.25– > 2 |  > 0.5 | 34.1 |
Tigecycline | 0.25–0.5 | 0.5 | 0.5 |  > 0.5 | 0.0 | 0.25–4 |  > 0.5 | 20.5 | |