From: Streptococcal and Staphylococcus aureus prosthetic joint infections: are they really different?
Treatment strategy |
Streptococcal PJIs (n = 86) |
MSSA PJIs (n = 123) | P |
---|---|---|---|
Exchange arthroplasty | 51 (59)a | 79 (64) | 0.389 |
Time (days) to prosthesis exchange | 22 [5–196] | 92 [12–257] | 0.062 |
One-stage exchange | 50 (98) | 74 (94) | 0.670 |
Two-stage exchange | 1 (2) | 5 (6) | 0.404 |
DAIR | 14 (16) | 29 (24) | 0.306 |
Time to DAIR (days) | 5 [2–9] | 8 [4–12] | 0.042 |
Mobile device exchange | 8 (57) | 14 (48) | 0.51 |
Definitive prosthesis removal | 0 | 5 | 0.079 |
Antibiotics combined with surgery | |||
Treatment duration (days) | 87 [85–92] | 87 [64–92] | 0.444 |
IV duration (days) | 32 [29–36] | 33 [29–44] | 0.265 |
Beta-lactams > 14 days | 65 (76) | 85 (69) | < 0.0001 |
Rifampicin > 14 days | 29 (35) | 88 (73) | < 0.0001 |
Prolonged suppressive antibiotic therapy | 21 (24) | 10 (8) | 0.001 |
Initial IV antibiotics | 16 (55) | 8 (80) | 1.000 |
IV duration (days) | 9 [4-23] | 16 [11–27] | 0.071 |
Duration (days) | 405 [375–741] | 366 [136–640] | 0.016 |