Table 1 General characteristics of patients

Sex

Female

36

48

36

120 (60)

Age

M (P25-P75)

58 (42–72)

59 (48–68)

49 (43–61)

–

Weight

M (P25-P75)

56.6 (50–66)

58.6 (50–65)

58.6 (54–65)

–

Period of treatment

1 week

26

36

17

79 (39.5)

2 weeks

22

28

22

72 (36)

3 weeks

18

19

12

49 (24.5)

Department

Infectious Diseases

6

24

44

74 (37)

Hematology

36

20

1

57 (28.5)

ICU

2

13

1

16 (8)

Respiratory

4

12

4

20 (10)

Nephrology

3

2

0

5 (2.5)

Rheumatology and Immunology

2

2

0

4 (2)

Others

13

10

1

24 (12)

Underlying disease

Cirrhosis of the liver

0

10

41

51 (25.5)

Haematological malignancy

34

19

1

54 (27)

Severe pulmonary disease

11

24

2

37 (18.5)

Cancer

6

14

0

20 (10)

Sepsis

1

0

5

6 (3)

Acute pancreatitis

1

3

1

5 (2.5)

Solid organ transplantation

4

0

0

4 (2)

Autoimmune disease

3

2

0

5 (2.5)

Chronic kidney disease

2

1

0

3 (1.5)

Atherosclerotic vascular disease

2

1

0

3 (1.5)

Others

2

9

1

12 (6)

Risk-factor for fungal infection

Broad-spectrum antibiotic

64

81

51

196 (98)

Corticosteroid

39

42

2

83 (41.5)

Immunosuppression

25

19

2

46 (23)

Central venous line

31

42

33

106 (53)

Recent surgery

5

12

1

18 (9)

Tracheal intubation

8

31

6

45 (22.5)

Malignancy

6

14

2

22 (11)

Diabete

12

12

4

28 (14)

Transplant recipient

4

0

0

4 (4)

HIV

0

2

1

3 (1.5)

Hepatoprotective drugs

Yes

35

60

48

143 (71.5)

Diagnostic grades of IFI

Infection site

Confirmed

2

8

2

12 (6)

Clinical diagnosis

31

47

36

114 (57)

Suspected diagnosis

33

28

13

74 (37)

Pulmonary

54

58

27

139 (69.5)

Digestive tract

10

16

22

48 (24)

Blood

1

5

1

7 (3.5)

Urinary tract

0

1

1

2 (1)

Others

1

3

0

4 (2)