Fig. 3

Testing MDW as a tier 1 assay of MIS-C. A Validation cohort: Blood samples were prospectively collected to assess an MDW threshold of 24 for identifying MIS-C. MDW was quantified in children with MIS-C, other infectious illnesses, non-infection illnesses, and healthy controls. Analysis by ordinary one-way ANOVA. ****P < 0.0001. B ROC in the validation cohort to assess the utility of MDW as a screening tool for MIS-C. AUC = area under the curve (percentage). Two outliers identified by Grubb’s outlier test in the healthy control and infection-inflammation groups were removed for analysis