Table 4 Baseline laboratory predictors of outcome in among People with HIV (PWH, n = 270)
Parameter* | Survivors n = 199 (73.7%) | Non-survivors n = 71 (26.3%) | COR** (95% CI) | P value |
|---|---|---|---|---|
CD4 (n = 222) | 1.92 (1.03–3.56) | 0.04 | ||
≥ 200 (n = 147) | 116 (78.9%) | 31 (21.1%) | ||
< 200 (n = 75) | 49 (65.3%) | 26 (34.7%) | ||
HIV viral load (n = 262) | 1.70 (0.82–3.5) | 0.15 | ||
< 1000 (n = 204) | 146 (71.6%) | 58 (28.4%) | ||
> 1000 (n = 58) | 47(81.0%) | 11 (19.0%) | ||
PaO2 (kPa) (n = 150) | 8.8 (6.5–11.7) | 7.2 (5.9–10.5) | 0.97 (0.91–1.04) | 0.39 |
FiO2 (%) (n = 178) | 0.21 (0.21–0.4) | 0.4 (0.21–0.8) | 5.34 (1.53–18.63) | 0.01 |
P:F ratio (n = 147) | 264.3 (159.9–344.2) | 172.5 (84–242.8) | 0.997 (0.983–1.010) | 0.64 |
WBC (n = 269) | 8.3 (6.12–11.1) | 10.23 (8.4–14.0) | 1.093 (1.036–1.154) | 0.001 |
N:L ratio (n = 227) | 4.0 (1.45–6.7) | 6.6 (4.2–11.8) | 1.12 (1.06–1.19) | < 0.001 |
CRP (n = 214) | 145 (77–240.5) | 247 (151.5–336) | 1.005 (1.002–1.007) | < 0.001 |
Creatinine (μmol/L) (n = 266) | 71 (53.25–96.75) | 89.5 (63.75–275) | 1.003 (1.001–1.004) | < 0.001 |
Haemoglobin (g/dL) (n = 266) | 12.7 (10.8–13.8) | 12.3 (9.3–13.5) | 1.021 (0.99–1.05) | 0.15 |
HbA1c (%) (n = 81) | 7.5 (6.8–8.4) | 7.0 (6.0–8.3) | 0.98 (0.95–1.02) | 0.42 |
Neutrophils (× 109/L) (n = 225) | 5.74 (3.95–8.34) | 8.25 (6.35–11.65) | 1.102 (1.04–1.17) | 0.002 |
Lymphocytes (× 109/L) (n = 227) | 1.57 (1.08–2.03) | 1.18 (0.77–1.78) | 0.51 (0.31–0.8) | 0.004 |
Platelets (× 109/L) (n = 265) | 268 (212.3–357.75) | 276 (197–367) | 0.289 | |
D-dimer (mg/L) (n = 52) | 0.61 (0.35–2.36) | 0.88 (0.54–6.81) | 1.15 (0.98–1.33) | 0.78 |