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Table 1 Characteristics of the patients in the previous and current case report studies

From: Concurrent severe pulmonary tuberculosis with Evans syndrome: a case report with literature review

Article Patient Presentation Laboratory findings Imaging studies Bacteriology Treatment Outcome
Kim et al. [10] 52-year-old man with a history of Evans syndrome Expanding perianal ulcer Hemoglobin: 11.2 g/dL, hematocrit: 34.6%, white blood count: 6900/μL, platelet: 97,000/μL Chest X-ray: irregular densities and infiltration in both upper lung fields Sputum and wound smear: acid-fast bacilli. Culture grew M. tuberculosis Isoniazid, rifampin, ethambutol, pyrazinamide Ulcer healed
Morell et al. [11] 25-year-old woman Left axillary lymphadenopathy, thrombopenia Platelet count changed from 86,000/μL to 7000/μL in 2 days, hemoglobin: 12.5 g/dL, hematocrit: 41%, white blood count: 8500/μL, Positive Coombs test after gamma globulin treatment Normal chest X-ray and chest/abdominal/pelvic CT scan Lymph node biopsy confirmed acid-fast bacilli and Mycobacterium tuberculosis Gamma globulin, Antitubercular quadritherapy Recovered
Sharma et al. [12] 30-year-old woman Fever, weight loss, petechiae, purpura Hemoglobin: 48 g/dL, platelet: 5000/μL, positive Coombs test X-ray/CT: infiltration in bilateral middle lung fields, necrotic mediastinal and mesenteric nodes Sputum smear revealed acid-fast bacilli Category 1 antitubercular therapy, hydroxychloroquine, methylprednisolone, and then corticosteroids Recovered
Shi et al. [13] 26-year-old pregnant woman, with a history of Evans syndrome Cough, fever, dyspnea Hemoglobin: 101 g/dL, platelet: 73,000/μL, white cell count: 13,860/μL, negative Coombs test Chest X-ray/CT: diffuse bilateral infiltration and pleural effusion. Abdominal CT splenomegaly Sputum PCR showed M. tuberculosis Mechanical ventilation, antituberculosis therapy (isoniazid, rifampin, ethambutol, pyrazinamide, moxifloxacin), methylprednisolone, plasma exchange Fetal demise, patient recovered
Gyawali et al. [14] 20-year-old man Melena, fever Hemoglobin: 5.3 g/dL, white blood count: 5400/μL, platelet: 319,000/μL, positive Coombs test Chest X-ray/CT: multiple centriacinar nodules, right pleural effusion Sputum negative for acid-fast bacilli Isoniazid, rifampin, pyrazinamide, ethambutol, prednisone Increased fatigue, weakness after stopping prednisone, recovered after methylprednisone and cyclosporine
Current case 69-year-old woman Fever, shortness of breath Hemoglobin: 7.3 g/dL, white blood count: 4900/μL, platelet: 160,000/μL Chest X-ray/CT: bilateral diffuse patchy infiltration and miliary nodules Sputum smear result of acid-fast bacilli: 3+ Isoniazid, rifapentine, sulbactam/cefoperazone Recovered
  1. CT computed tomography